Sequence 1: | NP_001262037.1 | Gene: | fz2 / 40090 | FlyBaseID: | FBgn0016797 | Length: | 806 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_032083.3 | Gene: | Fzd7 / 14369 | MGIID: | 108570 | Length: | 572 | Species: | Mus musculus |
Alignment Length: | 642 | Identity: | 282/642 - (43%) |
---|---|---|---|
Similarity: | 369/642 - (57%) | Gaps: | 121/642 - (18%) |
- Green bases have known domain annotations that are detailed below.
Fly 6 LKVLILGLV-LLLTSCRADGPLHSADHGMGGMGMGGHGLDASPAPGYGVPVIPKDPNLRCEEITI 69
Fly 70 PMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLP 134
Fly 135 VCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSG 199
Fly 200 SGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNP-QGEKASGKECSCSCRSPLIF 263
Fly 264 LGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGP-------FFSNDEKDFAGLWI 321
Fly 322 ALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIAC------ 380
Fly 381 DGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAW 445
Fly 446 LIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIR 510
Fly 511 SVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDW--------IKAL 567
Fly 568 ACPCAQVKGPG----KKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRL 620 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
fz2 | NP_001262037.1 | CRD_FZ5_like | 63..182 | CDD:143565 | 60/118 (51%) |
Frizzled | 308..618 | CDD:279827 | 180/327 (55%) | ||
Fzd7 | NP_032083.3 | CRD_FZ7 | 45..169 | CDD:143575 | 63/163 (39%) |
7tmF_FZD7 | 241..571 | CDD:320374 | 182/332 (55%) | ||
TM helix 1 | 250..275 | CDD:320374 | 13/24 (54%) | ||
TM helix 2 | 284..305 | CDD:320374 | 14/21 (67%) | ||
TM helix 3 | 335..361 | CDD:320374 | 19/25 (76%) | ||
TM helix 4 | 378..394 | CDD:320374 | 9/15 (60%) | ||
TM helix 5 | 416..445 | CDD:320374 | 21/28 (75%) | ||
TM helix 6 | 465..492 | CDD:320374 | 21/26 (81%) | ||
TM helix 7 | 521..546 | CDD:320374 | 11/24 (46%) | ||
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 550..555 | 3/4 (75%) | |||
PDZ-binding | 570..572 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X126 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |