Protein Alignment fz2 and LOC1271960

DIOPT Version :10

• Sequence 1: NP_001401042.1
• Gene: fz2 / 40090
• FlyBaseID: FBgn0016797
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_061513840.1
• Gene: LOC1271960 / 1271960
• VectorBaseID: AGAMI1_011497
• Length: 1187
• Species: Anopheles gambiae
• Alignment Length: 733
• Identity: 148/733 - (20%)
• Similarity: 238/733 - (32%)
• Gaps: 189/733 - (25%)

  Fly    33 MGGMGMGGHGLDASPAPGYGVPVIPKD-----------PNLRCEEITIPMCRGIGYNMTSFPNEM 86
            :.|.|....|..:||..|       ||           |..:||.:.:..||.:|||:|::||..
Mosquito   462 VSGTGDDIVGTSSSPLGG-------KDEVTVEIVTTARPPRKCEPLRLGYCRSVGYNVTTYPNFF 519

  Fly    87 NHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPIC-LEDYHKPL--PVCRSVCERARSGCA 148
            .|.:.:|...::..|..||:.:|......|:|.:..|.| .....:|.  .|||..|:...:||.
Mosquito   520 GHGSLEEVEADLISFRELVDAECFRQAFDFICRLLQPPCEYRSIEEPTAGTVCRQYCQSFWAGCG 584

  Fly   149 PIMQQYSFEWPERMA----CEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRK 209
            ..:       |||:.    ||..| .......|..:|..|    |.....:..|....|......
Mosquito   585 ERL-------PERLRRYLDCERFP-ESTGVQSCHSKPGCT----GELQANALSSRLCDGVADCAD 637

  Fly   210 QGGSGSGGSGAGGSSGSTSTKPCRGRNSK-----NCQNPQGEKASGKECSCSCRSPLIFLGKEQL 269
            .....:....|.|:.....::.|..||::     :|.:...||      .|...||
Mosquito   638 LSDENTCTFCAYGAISCGRSRACYARNARCDGKLDCPDGSDEK------DCLSISP--------- 687

  Fly   270 LQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSN-----DEKDFAGLWIALWSGLCF 329
                 |:..:..|               |.. :|.:..|:|.     .||...|.         .
Mosquito   688 -----QVSFLTFP---------------PPI-VPFRPRFYSEGYAVFSEKGTTGK---------L 722

  Fly   330 CSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTG--- 391
            ||..|....::.:|          |..|.|   .|:||...::   .||..|    .|.:|.
Mosquito   723 CSVGMEGNEYVRNT----------VAESLC---KALGYERVDY---SEIRND----TEPNTSYVR 767

  Fly   392 ---PHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSV 453
               |.:..:.|:.|......|         .:...:.|:.|.::....||...|:....|.....
Mosquito   768 VLDPRASEISFVRTQCQSKQS---------LYVACSHLECGVQSTLPTSQNIGLSKMATPGDWPW 823

  Fly   454 AVLLLSA---------VDGDPILGI--CYVGNLNPDHLKTFVLAPLFVYLVIGTTFLM--AGFVS 505
            .|.||.|         |..|.:|..  |:.|......:..|           |...|.  |.:..
Mosquito   824 HVALLRADTHVCDGTLVSKDWVLTTESCFQGQAKATWMAVF-----------GAVRLSSNAPWTQ 877

  Fly   506 LFRIRSVIKQ--QGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALA 568
            ..||..::|.  :|...|          |:|:          .|.|:         :.|:::.:.
Mosquito   878 RRRIIGMVKSPVEGSTAA----------MVRL----------ETPVV---------YSDFVRPIC 913

  Fly   569 CPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLG----APDRTGA 629
            .|...:|....:...||....:....:.|..|...: .|:.|:.:|::: .:.|    |.|..|.
Mosquito   914 LPDLPLKETIDRSDNSVTPTPHAEKYSTGGKSSKAV-VGRKLKEYRQYF-EMPGEDELAADEYGD 976

  Fly   630 NQALIKQRPPIPHPYAGSGMGMPVGSAA-GSLLATPYTQAGGASVASTSHHHLHHHVLKQPAASH 693
            .....|........:|.....:|...|| |.:...|......|.|.|.::....:........|.
Mosquito   977 LNEAAKYVNQYSADFADEQYHIPQAEAAVGPVQGRPTPSPPSAGVPSAAYPLPANSPQTNNYISA 1041

  Fly   694 VXHGESGGASTMGGGGGG 711
            : :..||||:.:|..|||
Mosquito  1042 LNYISSGGAANVGAPGGG 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001401042.1	CRD_FZ5_like	63..182	CDD:143565	34/125 (27%)
		7tmF_FZD5_FZD8-like	307..618	CDD:320163	62/336 (18%)
		TM helix 1	316..341	CDD:320163	4/24 (17%)
		TM helix 2	350..371	CDD:320163	6/20 (30%)
		TM helix 3	396..422	CDD:320163	3/25 (12%)
		TM helix 4	439..455	CDD:320163	2/15 (13%)
		TM helix 5	477..506	CDD:320163	4/30 (13%)
		TM helix 6	531..558	CDD:320163	4/26 (15%)
		TM helix 7	579..604	CDD:320163	4/24 (17%)
LOC1271960	XP_061513840.1	None