DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CNPYb and cnpy4

DIOPT Version :9

Sequence 1:	NP_649089.2	Gene:	CNPYb / 40084	FlyBaseID:	FBgn0036847	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_001034602.1	Gene:	cnpy4 / 568776	ZFINID:	ZDB-GENE-060315-5	Length:	217	Species:	Danio rerio

Alignment Length:	207	Identity:	97/207 - (46%)
Similarity:	140/207 - (67%)	Gaps:	7/207 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VTLWVVLQLAGADSPEEEQGVRYANRCEACKILATELEARLGETGKSHDVIEIGYSVDDVKPKKR 74
            |.|:.:..|..|:..|     |..|:||.||:|..||:..|.:||:|.:|:|:|..:|..|.:::
Zfish     6 VFLFYMFSLVLANQEE-----RLPNKCEVCKLLTVELQDALDKTGRSKEVVELGEVLDTGKRRRK 65

  Fly    75 TEYRRSELRLLESLENVCERVLEYNLHKERSDSTRFAKGMSQTFQTLHGLVDKGVKVDLGIPYEL 139
            .:|..||:||.|:::|:|||:|:|.:|.||..|.|:|||.|||..||..||:|||||:||:||||
Zfish    66 IKYNTSEMRLTEAMDNICERILQYKVHAERPGSLRYAKGTSQTMNTLKNLVEKGVKVELGVPYEL 130

  Fly   140 WDKPPVEVTQMKTQCENLLEEYEETISEWYFKHQDEKSLKKHLCEDHVLKKKAERECLKEQLAPP 204
            ||:|.|||.::|.|||.:|||:||.:.:|||.||| |.|::..||.||| |.:::|||.|.....
Zfish   131 WDEPTVEVAELKRQCETMLEEHEEVVEDWYFHHQD-KGLERFFCEAHVL-KDSDQECLTEIWKGD 193

  Fly   205 EAKKAKREKAKG 216
            ...|...|:::|
Zfish   194 MGMKGSEEESEG 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CNPYb	NP_649089.2	DUF3456	35..184	CDD:288766	77/148 (52%)
cnpy4	NP_001034602.1	DUF3456	26..174	CDD:288766	77/148 (52%)
cnpy4	NP_001034602.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..217		3/12 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580792
Domainoid	1	1.000	189	1.000	Domainoid score	I3229
eggNOG	1	0.900	-	-		E1_KOG4052
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15196
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3738
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1412562at2759
OrthoFinder	1	1.000	-	-		FOG0003994
OrthoInspector	1	1.000	-	-		oto40489
orthoMCL	1	0.900	-	-		OOG6_105615
Panther	1	1.100	-	-	LDO	PTHR15382
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3184
SonicParanoid	1	1.000	-	-		X2756
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.790