DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MESR6 and RGD1306502

DIOPT Version :9

Sequence 1:	NP_001262033.1	Gene:	MESR6 / 40083	FlyBaseID:	FBgn0036846	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_001101124.1	Gene:	RGD1306502 / 310158	RGDID:	1306502	Length:	434	Species:	Rattus norvegicus

Alignment Length:	440	Identity:	141/440 - (32%)
Similarity:	206/440 - (46%)	Gaps:	100/440 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 RHFQRIPVFIVDYHNDVLEFIYRCFATRHLPLQNNTLVHFDSHPDLVIPRHIAASSTYQKETMLN 156
            |.:.|:||::|:.|.:||.||||...::|||..|...:||||||||:||.::.|.:.:.||.:..
  Rat    12 RRYPRLPVWVVEDHQEVLPFIYRAIGSKHLPDSNIRFLHFDSHPDLLIPVNMPADTVFDKEALFG 76

  Fly   157 ELSIENWIMPTLYAEIENNVKGQIKKFYGHFNRVVWLKNSWCQQLPTGRHDFKVGQKD---DRIG 218
            ||||||||||.:||              |||:.|:||..:|.||:..|:|.|.|| ||   ..|.
  Rat    77 ELSIENWIMPAVYA--------------GHFSHVIWLHPTWAQQIREGKHHFLVG-KDISTTTIR 126

  Fly   219 VDCPLDYFIADGNYCTTEDLQDAKSVELQV------------HDADN------------------ 253
            |.....||::||.:...:.|::.|.::|.|            .|.|:
  Rat   127 VTSTDYYFLSDGLFVPEDQLENQKPLQLDVIMVEPYKLCSNQDDGDSVSSTKKPRLALGGGESTV 191

  Fly   254 -------------ESLNP-----------------NEFL-TEKDAKGFVLDIDLDFFSTSNPFLE 287
                         :::.|                 .|.| ..|....|||||||||||..|||.|
  Rat   192 AADGDSCSEGHRGDAVTPRSDSCSGSQQSQGTASTGEILGMLKTGDAFVLDIDLDFFSVKNPFKE 256

  Fly   288 IYKDADCYNQLKEIFHFESVEKVKKSGTATIADYLATAERRQTQLDALKTIFWHL----EEERNF 348
            ::.. |.|..|:|::.|:     |.....|..|.:...:.|..||:.|:.||..|    .||...
  Rat   257 MFTQ-DEYKILQELYQFK-----KPDSNLTEEDLVDVVDARTHQLEDLEAIFADLCDGDSEETVR 315

  Fly   349 EGLEKPDETVVTPEVYAKIVKLADQLQEKYPDDEIDWHLIFDSGSTTDNNGLPHHISIAEELETY 413
            :....|....:.|.|.:...::      :.|    |:.::..:|.|.|.:.||||||..||:|..
  Rat   316 KWASNPGMESLVPLVQSLTSRM------EVP----DYEMVHQAGLTCDYSELPHHISTEEEIEYL 370

  Fly   414 FANFKRFLQRLPVPPVAITMAHSAQDDYCPQDQVAFIEECVLRLLKEVFG 463
            ..:....|:.|| .|..:|:|.|:.|||||.:||..|:..||.:|..::|
  Rat   371 IQSVYSLLKSLP-KPTLVTIARSSLDDYCPPEQVDIIQGKVLDVLGSLYG 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MESR6	NP_001262033.1	UPF0489	99..279	CDD:289412	78/243 (32%)
RGD1306502	NP_001101124.1	UPF0489	19..169	CDD:289412	64/164 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349065
Domainoid	1	1.000	124	1.000	Domainoid score	I5423
eggNOG	1	0.900	-	-		E1_28PEW
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10149
Inparanoid	1	1.050	172	1.000	Inparanoid score	I4010
OMA	1	1.010	-	-		QHG59382
OrthoDB	1	1.010	-	-		D1501156at2759
OrthoFinder	1	1.000	-	-		FOG0007487
OrthoInspector	1	1.000	-	-		oto97719
orthoMCL	1	0.900	-	-		OOG6_107534
Panther	1	1.100	-	-	LDO	PTHR13225
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5613
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770