DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and SDP1

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_012153.1	Gene:	SDP1 / 854693	SGDID:	S000001375	Length:	209	Species:	Saccharomyces cerevisiae

Alignment Length:	157	Identity:	40/157 - (25%)
Similarity:	77/157 - (49%)	Gaps:	23/157 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 YNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKY--VLNVTPDLPNKFKESGDIKYLQIPITD-- 271
            |.:.|:.::|..::|       .||...|..:.:  |:||.       :|:.|:: :|:|..:
Yeast    56 YPKGPLLVLPEKIYL-------YSEPTVKELLPFDVVINVA-------EEANDLR-MQVPAVEYH 105

  Fly   272 HY----SQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMV 332
            ||    ...:|:..|.....|..|.:....:|:||..|:|||.|:.:||:|....|||..::.::
Yeast   106 HYRWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLL 170

  Fly   333 RDRKPDVSPNFHFMQQLLSFESQLRLR 359
            :.|...::|:...:.||:.:|..|..:
Yeast   171 KSRADKINPSIGLIFQLMEWEVALNAK 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	37/145 (26%)
		CDC14	<242..359	CDD:225297	33/124 (27%)
SDP1	NP_012153.1	DSP_fungal_SDP1-like	56..194	CDD:350371	39/152 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I2289
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9172
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10159
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.040