DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and PPS1

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_009835.3	Gene:	PPS1 / 852579	SGDID:	S000000480	Length:	807	Species:	Saccharomyces cerevisiae

Alignment Length:	185	Identity:	43/185 - (23%)
Similarity:	67/185 - (36%)	Gaps:	55/185 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 LFLGNATHSCDSEALKKYNIKYVLNV--------------TPDLPNK------------------ 255
            |:||:..|:.:...||...|.::::|              .|..|::
Yeast   593 LYLGSLDHAQNPALLKSLGITHIVSVGEVVSWTLNKDKIAHPVRPHRAITMTNTNEVAGNTTCNK 657

  Fly   256 --------------------FKESGDIKYLQIPITDHYSQDLAIHFPD-AIQFIEEARSASSVVL 299
                                ..|:...:..||...|...:|...|..| .:.||..:.:....||
Yeast   658 SRNRADTVVSDKQENGSNVVISENSGFQICQIENLDDNGKDPLFHQIDKVLDFISNSEATGGKVL 722

  Fly   300 VHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDV--SPNFHFMQQLLSF 352
            |||:.|||||.||.:|..|......|..|:..||.|:.:|  .||..|:.:|..:
Yeast   723 VHCMVGVSRSATVCIAECMRYLQCDLASAYLFVRVRRLNVIIQPNLFFVYELFKW 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	43/185 (23%)
		CDC14	<242..359	CDD:225297	37/166 (22%)
PPS1	NP_009835.3	DSP_fungal_PPS1	580..779	CDD:350366	43/185 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030