DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mkp3 and dusp27

DIOPT Version :10

Sequence 1:NP_001262031.1 Gene:Mkp3 / 40081 FlyBaseID:FBgn0036844 Length:497 Species:Drosophila melanogaster
Sequence 2:NP_001373589.1 Gene:dusp27 / 792623 ZFINID:ZDB-GENE-140513-1 Length:1100 Species:Danio rerio


Alignment Length:288 Identity:73/288 - (25%)
Similarity:123/288 - (42%) Gaps:37/288 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 EAPV----EIIPGLLFLGNATHSCDSEALKKYNIKYVLNV-------TPDLPNKFKESGDIKYLQ 266
            |||:    |:.|. :|:...:.:.:...||:..|.:|||.       |..|   |....:|.|:.
Zfish   137 EAPLSPVDEVWPN-VFIAEKSVAVNKGRLKRLGITHVLNAAHGTGVYTGPL---FYSGMNIHYMG 197

  Fly   267 IPITDHYSQDLAIHFPDAIQFIEEA-RSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFA 330
            |.:.|....|::.||....:|:::| .:....|||..:.|||||..:..||||..:.:|:.:|..
Zfish   198 IEVDDFPDADISPHFRSCAEFLDDALLTHRGKVLVDSMMGVSRSAVLVAAYLMIFQNMSIMEALL 262

  Fly   331 MVRDRKPDVSPNFHFMQQLLSFESQLRLRPGSRFSCSCIAPDCNCMQTTGFMATHLANATGVSPD 395
            .:| :|..:|||..|::||......| :..........:: .|:.:...|.:... .:..||..|
Zfish   263 EIR-KKRAISPNEGFIKQLRQLNETL-MEERDEDDDETLS-QCSVIDARGRLEEQ-ESVFGVKAD 323

  Fly   396 SGIEFDRWTPSDTGLKXEQSGGKSFVLPPSQEVPFAAAATSPLPMCLAVNPDNMSPASTTSSSTS 460
            |.:           :: |:.||.|.:...:...  ||||......|.:..|:...||...|....
Zfish   324 SIM-----------VEEEEDGGGSVISSVASSA--AAAALRAGVQCGSQQPNMQQPADQPSLPGQ 375

  Fly   461 TTTTAEAVSVVEMV---QHRDQEMAEED 485
            |....:. .|..|:   |.|:::...||
Zfish   376 TREDEDG-DVDRMILEWQKRNEKYQSED 402

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mkp3NP_001262031.1 DSP_MapKP 8..148 CDD:238723
DSP_MKP_classII 215..352 CDD:350414 44/148 (30%)
dusp27NP_001373589.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
PTP_DSP_cys 133..288 CDD:475123 47/156 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 356..383 6/27 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 411..436
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 479..504
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..561
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 575..615
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 667..686
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 888..1060
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1075..1100
Blue background indicates that the domain is not in the aligned region.

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