DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mkp3 and dusp27

DIOPT Version :9

Sequence 1:NP_001262031.1 Gene:Mkp3 / 40081 FlyBaseID:FBgn0036844 Length:497 Species:Drosophila melanogaster
Sequence 2:NP_001373589.1 Gene:dusp27 / 792623 ZFINID:ZDB-GENE-140513-1 Length:1100 Species:Danio rerio


Alignment Length:288 Identity:73/288 - (25%)
Similarity:123/288 - (42%) Gaps:37/288 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 EAPV----EIIPGLLFLGNATHSCDSEALKKYNIKYVLNV-------TPDLPNKFKESGDIKYLQ 266
            |||:    |:.|. :|:...:.:.:...||:..|.:|||.       |..|   |....:|.|:.
Zfish   137 EAPLSPVDEVWPN-VFIAEKSVAVNKGRLKRLGITHVLNAAHGTGVYTGPL---FYSGMNIHYMG 197

  Fly   267 IPITDHYSQDLAIHFPDAIQFIEEA-RSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFA 330
            |.:.|....|::.||....:|:::| .:....|||..:.|||||..:..||||..:.:|:.:|..
Zfish   198 IEVDDFPDADISPHFRSCAEFLDDALLTHRGKVLVDSMMGVSRSAVLVAAYLMIFQNMSIMEALL 262

  Fly   331 MVRDRKPDVSPNFHFMQQLLSFESQLRLRPGSRFSCSCIAPDCNCMQTTGFMATHLANATGVSPD 395
            .:| :|..:|||..|::||......| :..........:: .|:.:...|.:... .:..||..|
Zfish   263 EIR-KKRAISPNEGFIKQLRQLNETL-MEERDEDDDETLS-QCSVIDARGRLEEQ-ESVFGVKAD 323

  Fly   396 SGIEFDRWTPSDTGLKXEQSGGKSFVLPPSQEVPFAAAATSPLPMCLAVNPDNMSPASTTSSSTS 460
            |.:           ::.|:.||.|.:...:...  ||||......|.:..|:...||...|....
Zfish   324 SIM-----------VEEEEDGGGSVISSVASSA--AAAALRAGVQCGSQQPNMQQPADQPSLPGQ 375

  Fly   461 TTTTAEAVSVVEMV---QHRDQEMAEED 485
            |....:. .|..|:   |.|:::...||
Zfish   376 TREDEDG-DVDRMILEWQKRNEKYQSED 402

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mkp3NP_001262031.1 DSP_MapKP 8..148 CDD:238723
DSPc 215..353 CDD:238073 44/149 (30%)
CDC14 <242..359 CDD:225297 39/124 (31%)
dusp27NP_001373589.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
PTP_DSP_cys 133..288 CDD:421693 47/156 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 356..383 6/27 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 411..436
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 479..504
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..561
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 575..615
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 667..686
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 888..1060
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1075..1100
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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