DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and Dusp21

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_082844.1	Gene:	Dusp21 / 73547	MGIID:	1920797	Length:	189	Species:	Mus musculus

Alignment Length:	138	Identity:	47/138 - (34%)
Similarity:	74/138 - (53%)	Gaps:	2/138 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 IPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDIKYLQIPITDHYSQDLAIHFPD 283
            |...||:.|:..:.|...|...:|..::||:.::.|.|.|  ||:|:|:|::|..:..|...|..
Mouse    24 ITASLFISNSAVANDKLTLSNNHITTIINVSAEVVNTFFE--DIQYVQVPVSDAPNSYLYDFFDP 86

  Fly   284 AIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDVSPNFHFMQQ 348
            ....|......:...|:||.||||||.|:.|||||....::|.||....:..:|.:.||..|.:|
Mouse    87 IADHIHGVEMRNGRTLLHCAAGVSRSATLCLAYLMKYHNMTLLDAHTWTKTCRPIIRPNNGFWEQ 151

  Fly   349 LLSFESQL 356
            |:.:|.:|
Mouse   152 LIHYEFKL 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	45/133 (34%)
		CDC14	<242..359	CDD:225297	41/115 (36%)
Dusp21	NP_082844.1	DSPc	20..156	CDD:238073	45/133 (34%)
Dusp21	NP_082844.1	Sufficient for mitochondrial localization	43..128		30/86 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940