Protein Alignment Mkp3 and Dusp6

DIOPT Version :10

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_080544.1
• Gene: Dusp6 / 67603
• MGIID: 1914853
• Length: 381
• Species: Mus musculus
• Alignment Length: 351
• Identity: 145/351 - (41%)
• Similarity: 208/351 - (59%)
• Gaps: 28/351 - (7%)

  Fly    13 WLQSQLRSLDSKDLILLDCRGSHEYSESHIRGAVNLCIPSIVLRRLAVGKIDLASTIKSPELKQR 77
            ||..|| .|.::.|:|:|||....|..|||..|:|:.||.|:||||..|.:.:.:.....|.:.|
Mouse    22 WLNEQL-ELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDR 85

  Fly    78 IQSGYKLCWFILYNGEGVPGQNQEIAGAGSLAVAMDSIISILHRRLKQDGCRVVALQDGFNNFRQ 142
            ..........:||: |.....|:...|        :|::.:|.::||.:|||...|:.||:.|:.
Mouse    86 FTRRCGTDTVVLYD-ENSSDWNENTGG--------ESVLGLLLKKLKDEGCRAFYLEGGFSKFQA 141

  Fly   143 AFPEWCEDDNQTHSKEIESSRNVQTDQL--MGLRSLRISTTQSDSACSSSAESS---DCESSSHH 202
            .|...||.:       ::.|.:..:..|  :||..||||   |||  ||..||.   |..|::..
Mouse   142 EFALHCETN-------LDGSCSSSSPPLPVLGLGGLRIS---SDS--SSDIESDLDRDPNSATDS 194

  Fly   203 HHHHSHHNYNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDIKYLQI 267
            ......::....||||:| .|:||.|..|.:.:.|:::.|||:|||||:|||.|:.:|:.||.||
Mouse   195 DGSPLSNSQPSFPVEILP-FLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQI 258

  Fly   268 PITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMV 332
            ||:||:||:|:..||:||.||:|||..:..||||||||:|||||||:||||....||:|||:.:|
Mouse   259 PISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIV 323

  Fly   333 RDRKPDVSPNFHFMQQLLSFESQLRL 358
            :.:|.::||||:||.|||.||..|.|
Mouse   324 KMKKSNISPNFNFMGQLLDFERTLGL 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	43/134 (32%)
		DSP_MKP_classII	215..352	CDD:350414	79/136 (58%)
Dusp6	NP_080544.1	DSP_MapKP	18..147	CDD:238723	43/134 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..203		7/28 (25%)
		DSP_MKP_classII	207..343	CDD:350414	79/136 (58%)