DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and Dusp14

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_062793.2	Gene:	Dusp14 / 56405	MGIID:	1927168	Length:	198	Species:	Mus musculus

Alignment Length:	142	Identity:	49/142 - (34%)
Similarity:	75/142 - (52%)	Gaps:	10/142 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 IPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPN----KFKESGDIKYLQIPITDHYSQDLAI 279
            |...||||.|:.:.:...|:...|..|:|.|.::||    :|      :|:::|:.|.....:.:
Mouse    30 ITSSLFLGRASVASNWHLLQARGITCVINATIEIPNFNWPQF------EYVKVPLADIPHAPIRL 88

  Fly   280 HFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDVSPNFH 344
            :|......|..........||||.||||||.|:.:||||....|.|.:|:..|:.|:|.:.||..
Mouse    89 YFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLG 153

  Fly   345 FMQQLLSFESQL 356
            |.:||:.:||||
Mouse   154 FWRQLIDYESQL 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	45/137 (33%)
		CDC14	<242..359	CDD:225297	42/119 (35%)
Dusp14	NP_062793.2	DUSP14	20..169	CDD:350420	49/142 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940