DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mkp3 and si:ch211-195b15.8

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_686342.1	Gene:	si:ch211-195b15.8 / 558079	ZFINID:	ZDB-GENE-131127-627	Length:	462	Species:	Danio rerio

Alignment Length:	336	Identity:	89/336 - (26%)
Similarity:	138/336 - (41%)	Gaps:	85/336 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 PVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVT---PDLPNKFKESGDIKYLQIPITDHYSQD 276
            |:..|...|:||..| ....:.|....|.|||:|:   |. |:...:|   :||:|||.|....|
Zfish    13 PLSRILPHLYLGAET-DVTQDGLSDRGISYVLSVSRCCPQ-PSFLPQS---QYLRIPIDDSLRDD 72

  Fly   277 LAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDVSP 341
            |....|.|:.||:.|.||...|||||.||:|||..:.:||:|::..:.|:.|:..|::|:|.:||
Zfish    73 LLPWIPQALHFIDGAMSAGCSVLVHCAAGISRSPALAVAYVMYSLKMDLDHAYRFVKERRPTISP 137

  Fly   342 NFHFMQQLLSFESQLRLR--------------PGS-RFSCSCIAP-----------DCNCM---Q 377
            ||:|:.||..|:..|.|:              |.| :.:.|..||           |.||:   :
Zfish   138 NFNFLGQLQLFQGTLSLKNNKSNLHALDNCPQPTSEKHNSSSTAPLLTNLNLQNNMDNNCIINGR 202

  Fly   378 TTGFMAT-HLANATG--------------VSPD----------------SGIEFDRWTPSDTGLK 411
            |....|. |..|...              :.|:                :..|..|  |::...:
Zfish   203 TEDSKANMHCENKNSQQENVQSRGQDYKLLKPEFTLSLSDKLSALTLRTNPAEVQR--PANVTSQ 265

  Fly   412 XEQSGGKSFVLPPSQ-EVPFAAAATSPLPMCL--------------AVNPDNMSPASTTSSSTST 461
            .:|...||.:..|:. ::|..|.....|.:.|              :||..::..:|.......|
Zfish   266 TQQDAPKSILAKPTHLQIPSLAEKRKSLTLSLTPASAVPQTPQKGSSVNSCDLKQSSPAGDQKGT 330

  Fly   462 TTTAEAVSVVE 472
            ......||.:|
Zfish   331 LDDRSRVSALE 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	55/140 (39%)
		CDC14	<242..359	CDD:225297	50/119 (42%)
si:ch211-195b15.8	XP_686342.1	DSPc	13..149	CDD:238073	55/140 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D389486at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920