DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and Dusp3

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_006247464.1	Gene:	Dusp3 / 498003	RGDID:	1560049	Length:	212	Species:	Rattus norvegicus

Alignment Length:	149	Identity:	48/149 - (32%)
Similarity:	79/149 - (53%)	Gaps:	12/149 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 EIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTP--------DLPNKFKESGDIKYLQIPITDHY 273
            |:|| .:::|||:.:.|...|:|..|.:|||...        ...:.:|::| |.|:.|...|..
  Rat    58 EVIP-RVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYKDTG-ITYMGIKANDTQ 120

  Fly   274 SQDLAIHFPDAIQFIEEARS-ASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKP 337
            ..:|:.:|..|..||::|.: .:..|||||..|.|||.|:.:||||..:.:.:..|.:.||..:
  Rat   121 EFNLSAYFERAADFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLMLRQKMDVRSALSTVRQNR- 184

  Fly   338 DVSPNFHFMQQLLSFESQL 356
            ::.||..|:.||.....:|
  Rat   185 EIGPNDGFLAQLCQLNDRL 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	47/144 (33%)
		CDC14	<242..359	CDD:225297	39/124 (31%)
Dusp3	XP_006247464.1	DSPc	55..200	CDD:238073	47/144 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910