DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and Dupd1

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_036014638.1	Gene:	Dupd1 / 435391	MGIID:	3647127	Length:	226	Species:	Mus musculus

Alignment Length:	214	Identity:	58/214 - (27%)
Similarity:	88/214 - (41%)	Gaps:	51/214 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 SACSSSAESSDCESSSHHHH-----------------------------------HHSHHNYNEA 214
            ::..|...|.|.::|..|.|                                   .::|.|
Mouse     6 TSLGSKMASGDTKTSVKHAHLCAERLSVREEEGDAEDYCTPGAFELERLFWKGSPQYTHVN---- 66

  Fly   215 PVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDL------PNKFKESGDIKYLQIPITDHY 273
              |:.| .|.:|:...:.|...|:|....:|||.....      |:.:::.. |:|..:...|..
Mouse    67 --EVWP-RLHIGDEATALDRYGLQKAGFTHVLNAAHGRWNVDTGPDYYRDMA-IEYHGVEADDVP 127

  Fly   274 SQDLAIHFPDAIQFIEEA-RSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKP 337
            :.||:|.|..|..||:.| |...|.:||||..|.|||.|:.|||||..:.::|.||...|...:
Mouse   128 TFDLSIFFYSAAAFIDSALRDDHSKILVHCAMGRSRSATLVLAYLMIHKNMTLVDAIQQVAKNR- 191

  Fly   338 DVSPNFHFMQQLLSFESQL 356
            .|.||..|::||...:.||
Mouse   192 CVLPNRGFLKQLRELDKQL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	48/144 (33%)
		CDC14	<242..359	CDD:225297	43/122 (35%)
Dupd1	XP_036014638.1	DUPD1	55..214	CDD:350423	52/165 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910