Protein Alignment Mkp3 and dusp1

DIOPT Version :10

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_998232.2
• Gene: dusp1 / 406340
• ZFINID: ZDB-GENE-040426-2018
• Length: 369
• Species: Danio rerio
• Alignment Length: 349
• Identity: 116/349 - (33%)
• Similarity: 177/349 - (50%)
• Gaps: 54/349 - (15%)

  Fly    16 SQLRSL---DSKDLILLDCRGSHEYSESHIRGAVNLCIPSIVLRRLAVGKIDLASTIKSPELKQR 77
            :.||.:   |..|.::||||....:|.|||.|:.|:...:|| ||.|.|.:.|...:.:.:.:.|
Zfish    21 ASLRDMLEGDDPDCLVLDCRSFFSFSVSHISGSSNVRFSTIV-RRRARGGLGLEHIVPNEDTRNR 84

  Fly    78 IQSG-YKLCWFI----LYNGEGVPGQNQEIAGAGSLAVAMDSIISILHRRLKQDGCRVVALQDGF 137
            :.|| |:...|:    |..|        |:...|:|.:|::::..      ||.|..|..|:.||
Zfish    85 LLSGEYQSVVFLDDHSLEMG--------EVKKDGTLMLAVNALCR------KQCGASVYLLKGGF 135

  Fly   138 NNFRQAFPEWCEDDNQTHSKEIESSRNVQTDQLMGLRSLRISTTQSDSACSSSAESSDCESSSHH 202
            :.|...|||.|                .:|....|| ||.:|     |.|.|:...|.|.:.:..
Zfish   136 DTFSAEFPEKC----------------TKTVPPQGL-SLPLS-----SNCHSNTADSSCNTCTTP 178

  Fly   203 HHHHSHHNYNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDIKYLQI 267
            .:...      .||||:| .|:||:|.|:...:.|....|..::||:.:.||.|::  ..:|..|
Zfish   179 LYDQG------GPVEILP-FLYLGSAYHASRKDMLDMLGITALINVSSNCPNHFED--HYQYKSI 234

  Fly   268 PITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMV 332
            |:.|::..:::..|.:||:||:..|:....|.|||.||:|||.|:.|||||.|..:.|.:||..|
Zfish   235 PVEDNHKANISSWFNEAIEFIDSVRNKGGRVFVHCQAGISRSATICLAYLMRTNRVKLEEAFEFV 299

  Fly   333 RDRKPDVSPNFHFMQQLLSFESQL 356
            :.|:..:||||.||.|||.||||:
Zfish   300 KQRRSIISPNFSFMGQLLQFESQV 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	43/139 (31%)
		DSP_MKP_classII	215..352	CDD:350414	57/136 (42%)
dusp1	NP_998232.2	DSP_MapKP	17..146	CDD:238723	43/139 (31%)
		DSP_DUSP1	185..336	CDD:350486	61/142 (43%)