DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and Dusp29

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001101838.1	Gene:	Dusp29 / 361003	RGDID:	1310229	Length:	215	Species:	Rattus norvegicus

Alignment Length:	158	Identity:	51/158 - (32%)
Similarity:	78/158 - (49%)	Gaps:	16/158 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 HSHHNYNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDL------PNKFKESGDIKY 264
            ::|.|      |:.| .|.:|:...:.|...|:|....:|||.....      |:.:::.. |:|
  Rat    51 YTHVN------EVWP-RLHVGDEATALDRYGLQKAGFTHVLNAAHGRWNVDTGPDYYRDMA-IEY 107

  Fly   265 LQIPITDHYSQDLAIHFPDAIQFIEEA-RSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDA 328
            ..:...|..:.||:|.|..|..||:.| :...|.:||||..|.|||.|:.|||||..:.::|.||
  Rat   108 HGVEADDVPTFDLSIFFYSAAAFIDSALQDDHSKILVHCAMGRSRSATLVLAYLMIHKNMTLVDA 172

  Fly   329 FAMVRDRKPDVSPNFHFMQQLLSFESQL 356
            ...|...: .|.||..|::||...:.||
  Rat   173 IQQVAKNR-CVLPNRGFLKQLRELDKQL 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	47/144 (33%)
		CDC14	<242..359	CDD:225297	42/122 (34%)
Dusp29	NP_001101838.1	DSPc	53..196	CDD:238073	49/151 (32%)
Dusp29	NP_001101838.1	Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q68J44	145..152		3/6 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910