Protein Alignment Mkp3 and Dusp4

DIOPT Version :9

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_795907.1
• Gene: Dusp4 / 319520
• MGIID: 2442191
• Length: 398
• Species: Mus musculus
• Alignment Length: 440
• Identity: 129/440 - (29%)
• Similarity: 202/440 - (45%)
• Gaps: 101/440 - (22%)

  Fly    27 ILLDCRGSHEYSESHIRGAVNLCIPSIVLRRLAVGKIDLASTIKS-PELKQRIQSGYKLCWFILY 90
            :|||||....:|..:|||:||:...:|| ||.|.|.:.|...:.: .|::.|::||       ||
Mouse    50 LLLDCRPFLAHSAGYIRGSVNVRCNTIV-RRRAKGSVSLEQILPAEEEVRARLRSG-------LY 106

  Fly    91 NGEGVPGQNQEIAGAGSLAVAMDSIISILHRRLKQDGCR--VVALQDGFNNFRQAFPEWCEDDNQ 153
            :...|..:....|.    ::..||.:|::.:.|:::..|  :..|:.|:..|...:||:|.
Mouse   107 SAVIVYDERSPRAE----SLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCS---- 163

  Fly   154 THSKEIESSRNVQTDQLMGL-RSLRISTTQS-DSACSSSAESSDCESSSHHHHHHSHHNYNEAPV 216
                        :|..|..: ..:..||.:| |..|||      |.:..|.         ...||
Mouse   164 ------------KTKALAAIPPPVPPSTNESLDLGCSS------CGTPLHD---------QGGPV 201

  Fly   217 EIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDIKYLQIPITDHYSQDLAIHF 281
            ||:| .|:||:|.|:...:.|....|..:|||:.|.||.|:  |..:|..||:.|::..|::..|
Mouse   202 EILP-FLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFE--GHYQYKCIPVEDNHKADISSWF 263

  Fly   282 PDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDVSPNFHFM 346
            .:||::|:..:.....|||||.||:|||.|:.|||||..:.:.|.:||..|:.|:..:||||.||
Mouse   264 MEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFM 328

  Fly   347 QQLLSFESQLRLRPGSRFSCSCIAPDCNCMQTTGFMATHLANATGVSPDSGIEFDRWTPSDTGLK 411
            .|||.||||:       .:.||.                   |...||...:
Mouse   329 GQLLQFESQV-------LTTSCA-------------------AEAASPSGPL------------- 354

  Fly   412 XEQSGGKSFVLPPSQEVPFAAAATSPLPMCLAVNPDNM----SPASTTSS 457
              :..||:...|.||.|     .:.|:.:.:...|.|:    ||.:|:.|
Mouse   355 --RERGKATPTPTSQFV-----FSFPVSVGVHAAPSNLPYLHSPITTSPS 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	36/123 (29%)
		DSPc	215..353	CDD:238073	59/137 (43%)
		CDC14	<242..359	CDD:225297	52/116 (45%)
Dusp4	NP_795907.1	DSP_MapKP	9..162	CDD:238723	36/123 (29%)
		DSPc	199..335	CDD:238073	59/138 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940