DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and pmp1

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_595205.1	Gene:	pmp1 / 2540019	PomBaseID:	SPBC1685.01	Length:	278	Species:	Schizosaccharomyces pombe

Alignment Length:	169	Identity:	46/169 - (27%)
Similarity:	84/169 - (49%)	Gaps:	24/169 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 HSHHNYNEAPVEIIPGLLFL-GNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESG----DIKY- 264
            :|:..|...||.|.|..::| ...|    ...::.:::  |:||..::.:.|:..|    |.|:
pombe    52 NSNQPYPNGPVCIYPPNIYLYAKPT----MPIIQSFDV--VINVAKEVLHPFRTDGRHYRDSKHN 110

  Fly   265 LQIPITDHYSQDLAIHFPDAIQFIEE-----------ARSASSVVLVHCLAGVSRSVTVTLAYLM 318
            |.|.:.||. :.:.||:....||..|           |...:..||::|..|:|||..:.:|::|
pombe   111 LDIQVFDHI-EYVHIHWDHDTQFALELDKLVSFVAYNAMQLNKKVLINCQMGISRSACLMIAFIM 174

  Fly   319 HTRGLSLNDAFAMVRDRKPDVSPNFHFMQQLLSFESQLR 357
            .|..|:::||:..|::|.|.:.||...:.||..::..:|
pombe   175 KTLNLNVSDAYEYVKERSPWIGPNMSLIFQLSEYQQIIR 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	43/154 (28%)
		CDC14	<242..359	CDD:225297	38/132 (29%)
pmp1	NP_595205.1	CDC14	35..227	CDD:225297	46/169 (27%)
pmp1	NP_595205.1	DSPc	61..209	CDD:238073	43/154 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10159
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040