Protein Alignment Mkp3 and Ssh2

DIOPT Version :10

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_006533290.1
• Gene: Ssh2 / 237860
• MGIID: 2679255
• Length: 1450
• Species: Mus musculus
• Alignment Length: 484
• Identity: 105/484 - (21%)
• Similarity: 174/484 - (35%)
• Gaps: 151/484 - (31%)

  Fly     2 PETEHETC-SKEWLQSQLRSLDSKDLILLDCRGSHEYSESHIRGAVN------------------ 47
            |.|....| |..:|:      ||:...||.|    ||.||.|....|
Mouse    12 PSTTSSPCASSSYLE------DSESAALLCC----EYGESEIFSDFNEADSGEEECRSQPRSISE 66

  Fly    48 --LCIPSIVL----------------RRLAVGKIDLASTIKS------PE----LKQRIQSGY-- 82
              |.:....|                |....|  ||...:::      ||    |..|::|.|
Mouse    67 SFLTVKGAALFLPRGNGSSTPRVSHRRNKHAG--DLQQHLQAMFILLRPEDNIRLAVRLESTYQN 129

  Fly    83 KLCWFILYNGEGVPGQNQEIA------------------------------GAGSLAVAMDSIIS 117
            :..:.::.:..|.....:.|.                              |.|..:|:.|:.:.
Mouse   130 RTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVH 194

  Fly   118 I---------------LHRRLKQDGCRVVALQDGF----------------NNFRQAFPEW-CED 150
            |               ||:     .|.|..:.:.:                |:.:.:..|| ...
Mouse   195 IFKPVSVQAMWSALQSLHK-----ACEVARMHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQ 254

  Fly   151 DNQTHS-------KEIESSRNVQTDQLMGLRSLRISTTQSDSACSSSAE-------SSDCESSSH 201
            |.|:|.       .:|.:.|. :|::|:..: ||....|.|....:|.|       ...|.....
Mouse   255 DVQSHRPDSPALFTDIPTERE-RTERLIKTK-LREIMMQKDLENITSKEIRTELEMQMVCNLREF 317

  Fly   202 HHHHHSHH----NYNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDI 262
            .....:..    ...::|.:|... :|||:..::.:.|.|:...::|:||||.::.|.|  .|..
Mouse   318 KEFIDNEMIVILGQMDSPTQIFEH-VFLGSEWNASNLEDLQNRGVRYILNVTREIDNFF--PGVF 379

  Fly   263 KYLQIPITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLND 327
            :|..|.:.|..:.||..::.|..:||.:|:...|..||||..|||||.:..:||.|...|.:|:.
Mouse   380 EYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDR 444

  Fly   328 AFAMVRDRKPDVSPNFHFMQQLLSFESQL 356
            |:..|::|:....||..||:||..::..|
Mouse   445 AYDYVKERRTVTKPNPSFMRQLEEYQGIL 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	40/250 (16%)
		DSP_MKP_classII	215..352	CDD:350414	48/136 (35%)
Ssh2	XP_006533290.1	SSH-N	40..263	CDD:212166	33/229 (14%)
		DEK_C	277..329	CDD:462592	9/52 (17%)
		DSP_slingshot_2	332..475	CDD:350417	49/145 (34%)