back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mkp3 and Dusp7

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_703189.3	Gene:	Dusp7 / 235584	MGIID:	2387100	Length:	422	Species:	Mus musculus

Alignment Length:	369	Identity:	155/369 - (42%)
Similarity:	207/369 - (56%)	Gaps:	35/369 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SKEWLQSQLRSLDSKDLILLDCRGSHEYSESHIRGAVNLCIPSIVLRRLAVGKIDLASTIKSPEL 74
            |.||||.:|.:.....|:|||||....:..|||..|:||.||.::||||..|.:.:.|.|.:...
Mouse    59 SAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD 123

  Fly    75 KQRIQSGYKLCWFILYNGEGVPGQNQEIAGAGSLAVAMDSIISILHRRLKQDGCRVVALQDGFNN 139
            |:|..:..|....:||:......|.:..|.|        |::.:|.::|:.|||:...||.|||.
Mouse   124 KERFATRCKAATVLLYDEATAEWQPEPGAPA--------SVLGLLLQKLRDDGCQAYYLQGGFNK 180

  Fly   140 FRQAFPEWCEDDNQTHSKEIESSRNVQTDQLMGLRSLRISTT----QSDSACSSSAESSD---CE 197
            |:..:.|.||    |:.....|........::||..||||:.    :||....|||..||   ..
Mouse   181 FQTEYSEHCE----TNVDSSSSPSGSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVP 241

  Fly   198 SSSHHHHHHSHHNYNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDI 262
            ||.           ...||:|:| .|:||.|..|.:.:.|.||.|||:|||||:|||.|:..|:.
Mouse   242 SSQ-----------PAFPVQILP-YLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEF 294

  Fly   263 KYLQIPITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLND 327
            .|.||||:||:||:|:..||:||.||:||||....||||||||:|||||||:||||....|||||
Mouse   295 TYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLND 359

  Fly   328 AFAMVRDRKPDVSPNFHFMQQLLSFESQLRLRPGSRFSCSCIAP 371
            |:..|:.:|.::||||:||.|||.||..|    |....|...||
Mouse   360 AYDFVKRKKSNISPNFNFMGQLLDFERTL----GLSSPCDNHAP 399

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.