Protein Alignment Mkp3 and Dusp1

DIOPT Version :9

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_038670.1
• Gene: Dusp1 / 19252
• MGIID: 105120
• Length: 367
• Species: Mus musculus
• Alignment Length: 456
• Identity: 135/456 - (29%)
• Similarity: 201/456 - (44%)
• Gaps: 118/456 - (25%)

  Fly    18 LRSL---DSKDLILLDCRGSHEYSESHIRGAVNLCIPSIVLRRLAVGKIDLASTIKSPELKQRIQ 79
            ||:|   .:...:|||||....::..||.|:||:...:|| ||.|.|.:.|...:.:.||:.|:.
Mouse    13 LRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIV-RRRAKGAMGLEHIVPNAELRGRLL 76

  Fly    80 SG-YKLCWFILYNGEGVPGQNQEIAGAGSLAVAMDSIISILHRRLKQDGCR------VVALQDGF 137
            :| |.....:......:.|..::    |:||:|..::            ||      |..||.|:
Mouse    77 AGAYHAVVLLDERSASLDGAKRD----GTLALAAGAL------------CREARSTQVFFLQGGY 125

  Fly   138 NNFRQAFPEWCEDDNQTHSKEIESSRNVQTDQLMGLRSLRISTTQSDSACSSSAESSDCESSSHH 202
            ..|..:.||.|            |.::..|    || ||.:||:..|||      .|.|.|.|..
Mouse   126 EAFSASCPELC------------SKQSTPT----GL-SLPLSTSVPDSA------ESGCSSCSTP 167

  Fly   203 HHHHSHHNYNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDIKYLQI 267
            .:...      .||||: ..|:||:|.|:...:.|....|..::||:.:.||.|:  |..:|..|
Mouse   168 LYDQG------GPVEIL-SFLYLGSAYHASRKDMLDALGITALINVSANCPNHFE--GHYQYKSI 223

  Fly   268 PITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMV 332
            |:.|::..|::..|.:||.||:..:.|...|.|||.||:|||.|:.|||||.|..:.|::||..|
Mouse   224 PVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFV 288

  Fly   333 RDRKPDVSPNFHFMQQLLSFESQLRLRPGSRFSCSCIAPDCNCMQTTGFMATHLANATGVSPDSG 397
            :.|:..:||||.||.|||.||||:            :||.|              :|...||...
Mouse   289 KQRRSIISPNFSFMGQLLQFESQV------------LAPHC--------------SAEAGSPAMA 327

  Fly   398 IEFDRWTPSDTGLKXEQSGGKSFVLPPSQEVPFAAAATSPLPMCLAVNPDN------MSPASTTS 456
            : .||.|.:.|...                          .|:.:.|:|.|      .||.:|:.
Mouse   328 V-LDRGTSTTTVFN--------------------------FPVSIPVHPTNSALNYLKSPITTSP 365

  Fly   457 S 457
            |
Mouse   366 S 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	39/139 (28%)
		DSPc	215..353	CDD:238073	58/137 (42%)
		CDC14	<242..359	CDD:225297	52/116 (45%)
Dusp1	NP_038670.1	DSP_MapKP	7..136	CDD:238723	39/139 (28%)
		DSPc	173..309	CDD:238073	58/138 (42%)
		CDC14	188..313	CDD:225297	54/138 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940