Protein Alignment Mkp3 and lip-1

DIOPT Version :9

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001293707.1
• Gene: lip-1 / 191704
• WormBaseID: WBGene00003043
• Length: 381
• Species: Caenorhabditis elegans
• Alignment Length: 416
• Identity: 127/416 - (30%)
• Similarity: 197/416 - (47%)
• Gaps: 68/416 - (16%)

  Fly     1 MPETEH--ETCSKEWLQSQLRSLDSKDLILLDCRGSHEYSESHIRGAVNLCIPSIVLRRLAVGKI 63
            :|.|..  |..|.|...   |....:::|:||||.:.:..:...|...:|.:|:::.|||..|.:
 Worm     5 LPSTSQNGEEISAEQFN---RIFHERNVIVLDCRSNGDSVKRANRFFCSLRLPALLQRRLMGGSM 66

  Fly    64 DLASTIKSPELKQRIQSGYKLCWFILYNGEGVPG---QNQEIAGAGSLAVAMDSIISILHRRLKQ 125
            .| ||:  |:||. :.:....|..:|.    :||   |:::::.|             |.|.||.
 Worm    67 RL-STV--PDLKD-LNNSPDQCPEVLL----IPGDSEQDEQLSAA-------------LARNLKS 110

  Fly   126 DGCRVVALQDGFNNFRQAFPEW--CEDDNQTHSKEIE------SSRNVQTDQLMGLRSLRISTTQ 182
            :..|...|.:........||..  ..|:|...:.::.      |.:...:..|:.|..||:
 Worm   111 NHYRHFVLGEPVKTLLSQFPTLRDAADENWNTTFQMNSMPGQASGQQASSGPLLNLNQLRL---- 171

  Fly   183 SDSACSSSAESSDCESSSHHHHHHSHHNYNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLN 247
                     |..|          .......|.||: :...|:||||..:.:.:.||||:|.:|:|
 Worm   172 ---------EGED----------QGGKQRAEFPVK-LTNFLYLGNAETAKNRDVLKKYSISHVIN 216

  Fly   248 VTPDLPNKFKESGDIKYLQIPITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTV 312
            ||.:|||.|:|..:::||:|...|:.|.:|...||:||.||::||...|..|||||||:|||||:
 Worm   217 VTSNLPNTFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTI 281

  Fly   313 TLAYLMHTRGLSLNDAFAMVRDRKPDVSPNFHFMQQLLSFESQLRL---RPGSRFSCSCIAPDC- 373
            .|||||.|...:|:.|:..|:.|...::||||||.||..:|..|.|   |.|:..|.:..:|.|
 Worm   282 CLAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLGLNSNRVGTYPSSAPRSPSCA 346

  Fly   374 ---NCMQTTGFMATHLANATGVSPDS 396
               ..:...|.:.|....:...||.|
 Worm   347 IEAAAVSQVGGLLTPPPTSCSASPQS 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	35/144 (24%)
		DSPc	215..353	CDD:238073	66/137 (48%)
		CDC14	<242..359	CDD:225297	58/119 (49%)
lip-1	NP_001293707.1	DSPc	185..322	CDD:238073	66/137 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159041
Domainoid	1	1.000	134	1.000	Domainoid score	I3125
eggNOG	1	0.900	-	-		E2759_KOG1717
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	152	1.000	Inparanoid score	I2951
Isobase	1	0.950	-	0	Normalized mean entropy	S2795
OMA	1	1.010	-	-		QHG52370
OrthoDB	1	1.010	-	-		D389486at33208
OrthoFinder	1	1.000	-	-		FOG0002164
OrthoInspector	1	1.000	-	-		oto18388
orthoMCL	1	0.900	-	-		OOG6_107960
Panther	1	1.100	-	-	LDO	PTHR10159
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X468
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.720