Protein Alignment Mkp3 and vhp-1

DIOPT Version :10

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001343753.1
• Gene: vhp-1 / 173904
• WormBaseID: WBGene00006923
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 484
• Identity: 122/484 - (25%)
• Similarity: 205/484 - (42%)
• Gaps: 122/484 - (25%)

  Fly     8 TCSKEWLQSQLRSLDSKDLILLDCRGSHEYSESHIRGAVNLCIPSIVLRRLAVGKID-------- 64
            ||.   |.:.:|......|: :||||..||:|||:|.::|.....::.|||...|:|
 Worm    15 TCG---LAALIREAPDTTLV-VDCRGFTEYNESHVRHSMNAFFSKLIRRRLFENKLDDNCLIHQL 75

  Fly    65 LASTIKSPELKQRIQSGYKLCWFILYNGEGVPGQNQEIAGAGSLAVAMDSIISILHRRLKQ-DGC 128
            ::.:....::.:::.       .:||..|..|..|:....:.:...:...|:.:|..||:. |..
 Worm    76 MSCSSGCTKMDEKLD-------LVLYAEEDKPRGNKRRIASCNAPESTAKIMRVLRERLEDTDKF 133

  Fly   129 R-VVALQDGFNNFRQAFPEWCEDDNQTHSKEIESSRNVQTDQLMGLRSLRISTTQSDSACSSSAE 192
            | |:.|:.||..|.|.:|:.||...                   |:..|..|.:|   .|.|...
 Worm   134 RSVMVLEGGFKQFAQQYPQLCESSE-------------------GMTRLPQSLSQ---PCLSQPT 176

  Fly   193 SSDCESSSHHHHHHSHHNYNEAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFK 257
            ...                    :.:|...::||:...|.|...|...:|..|:|::...|....
 Worm   177 GDG--------------------ITLITPNIYLGSQIDSLDETMLDALDISVVINLSMTCPKSVC 221

  Fly   258 ESGDIKYLQIPITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRG 322
            ...|..:::||:.|.|.:.|:.:||.|.:|:|:.|.|....|:|||||:|||.|:.::|:|....
 Worm   222 IKEDKNFMRIPVNDSYQEKLSPYFPMAYEFLEKCRRAGKKCLIHCLAGISRSPTLAISYIMRYMK 286

  Fly   323 LSLNDAFAMVRDRKPDVSPNFHFMQQLLSFESQLRLRPGSRFSCSCIAPDCNCMQTTGFMATHLA 387
            :..:||:..|::|:|.:||||:||.|||.:|:.|                         :..|:.
 Worm   287 MGSDDAYRYVKERRPSISPNFNFMGQLLEYENVL-------------------------IKDHVL 326

  Fly   388 NATGVS-PDSGIEFDRWTPSDTGLKXEQSGGKSFVLPPSQEVPFAAAATSPLPMCLAVNPDNMSP 451
            :....| |..  ..|.:.|||             :.||  :||.:|::....|   ....|..||
 Worm   327 DYNQASRPHR--HMDYYGPSD-------------LCPP--KVPKSASSNCVFP---GSTHDESSP 371

  Fly   452 AS-------------TTSSSTSTTTTAEA 467
            :|             |:||:.|:::||.|
 Worm   372 SSPSVSEGSAASEPETSSSAASSSSTASA 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	39/149 (26%)
		DSP_MKP_classII	215..352	CDD:350414	49/136 (36%)
vhp-1	NP_001343753.1	DSP_MapKP	12..154	CDD:238723	39/149 (26%)
		DSP_MKP_classIII	180..320	CDD:350416	50/139 (36%)