Protein Alignment Mkp3 and Dusp2

DIOPT Version :10

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_034220.2
• Gene: Dusp2 / 13537
• MGIID: 101911
• Length: 318
• Species: Mus musculus
• Alignment Length: 357
• Identity: 99/357 - (27%)
• Similarity: 158/357 - (44%)
• Gaps: 90/357 - (25%)

  Fly    22 DSKDLILLDCRGSHEYSESHIRGAVNLCIP-SIVLRRLAVG--KIDLASTIKSPELKQRIQSGYK 83
            :::..:|||||....:..||:|.|  ..:| :.:|||.|.|  ...||..:....|:.|:
Mouse    27 EAERTLLLDCRPFLAFCRSHVRAA--RPVPWNALLRRRARGTPAAALACLLPDRALRARL----- 84

  Fly    84 LCWFILYNGEGVPGQNQEIAGAGSL--AVAMDS----------------IISILHRRLKQDGCRV 130
                                |.|.|  ||.:|.                :::.|...::.....|
Mouse    85 --------------------GRGELARAVVLDESSASVAELPPDGPAHLLLAALQHEMRGGPTTV 129

  Fly   131 VALQDGFNNFRQAFPEWCEDDNQTHSKEIESSRNVQTDQLMGLRSLRISTTQSDSACSSSAESSD 195
            ..|:.||.:|:...|:.|                              |...:.:...:.||:|:
Mouse   130 CFLRGGFKSFQTYCPDLC------------------------------SEAPAQALPPAGAENSN 164

  Fly   196 CESSSHHHHHHSHHNYNE-APVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKES 259
            .:...        ..|:: .||||:| .|:||:..||.|.:.|:...|..||||:...||.|:
Mouse   165 SDPRV--------PIYDQGGPVEILP-YLYLGSCNHSSDLQGLQACGITAVLNVSASCPNHFE-- 218

  Fly   260 GDIKYLQIPITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLS 324
            |...|..||:.|:...:::..|.:||.||:..:::...|||||.||:|||.|:.||||:.:..:.
Mouse   219 GLFHYKSIPVEDNQMVEISAWFQEAISFIDSVKNSGGRVLVHCQAGISRSATICLAYLIQSHRVR 283

  Fly   325 LNDAFAMVRDRKPDVSPNFHFMQQLLSFESQL 356
            |::||..|:.|:..:||||.||.|||..|:|:
Mouse   284 LDEAFDFVKQRRGVISPNFSFMGQLLQLETQV 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	32/146 (22%)
		DSP_MKP_classII	215..352	CDD:350414	59/136 (43%)
Dusp2	NP_034220.2	DSP_MapKP	12..147	CDD:238723	32/146 (22%)
		DSP_DUSP2	174..317	CDD:350489	61/145 (42%)