Protein Alignment Mkp3 and DUSP15

DIOPT Version :10

• Sequence 1: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_016883143.1
• Gene: DUSP15 / 128853
• HGNCID: 16236
• Length: 335
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 79/316 - (25%)
• Similarity: 121/316 - (38%)
• Gaps: 85/316 - (26%)

  Fly   217 EIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDIKYLQIPITDHYSQDLAIHF 281
            :::|| |:|||...:.|.:.|.:..|.::::: .:.|....:  ||.||:||:.|.....:..||
Human     7 KVLPG-LYLGNFIDAKDLDQLGRNKITHIISI-HESPQPLLQ--DITYLRIPVADTPEVPIKKHF 67

  Fly   282 PDAIQFIEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDVSPNFHFM 346
            .:.|.||...|......||||.||:|||.|:..||:|...||...|....::..:|..:||..|.
Human    68 KECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFR 132

  Fly   347 QQLLSFESQLRLRPGSRFSC---------------SCIAPDCNCMQ----TTGFMATHLANATGV 392
            |||..|......:.||.|:.               |.:.|  ..:|    |||  |.|..:.|
Human   133 QQLEEFGWASSQKDGSGFATEDEDKEWPHRLAQQGSLLPP--ILLQALWLTTG--ARHRTSKT-- 191

  Fly   393 SPDSGIEFDRWTPS-----------DTGLKXEQSG-------------GKSFVLPPSQEVPFAAA 433
               ||.:....|.:           ...|..|.:|             .:..:.||    |..||
Human   192 ---SGAQCPPMTSATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAERLLGPP----PHVAA 249

  Fly   434 ATSPLP---MCLAVNPDNMSPASTTSSSTSTTTTAEAVSVVEMVQHRDQEMAEEDI 486
            ..||.|   :||....::..|                      .||..:::...|:
Human   250 GWSPDPKYQICLCFGEEDPGP----------------------TQHPKEQLIMADV 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSP_MKP_classII	215..352	CDD:350414	46/134 (34%)
DUSP15	XP_016883143.1	DSP_DUSP15	1..145	CDD:350430	47/141 (33%)