DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mkp3 and dusp28

DIOPT Version :9

Sequence 1:	NP_001262031.1	Gene:	Mkp3 / 40081	FlyBaseID:	FBgn0036844	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_001344320.3	Gene:	dusp28 / 100005205	ZFINID:	ZDB-GENE-131127-257	Length:	156	Species:	Danio rerio

Alignment Length:	144	Identity:	47/144 - (32%)
Similarity:	76/144 - (52%)	Gaps:	4/144 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 LFLGNATHSCDSEALKKYNIKYVLNVTPDLPNKFKESGDIKYLQIPITDHYSQDLAIHFPDAIQF 287
            |.:.||..:|:::.::|..:...:||:...|   ..|..:..|::|:.|..::||..:|......
Zfish    11 LLISNARSACNNDLIQKEAVTLCINVSKQQP---FPSARVSTLRVPVYDDPNEDLYRYFDRCADA 72

  Fly   288 IEEARSASSVVLVHCLAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDVSPNFHFMQQLLSF 352
            |..........:|:|..|.|||.||.:||||..:.|:|.|||.:|:..:..|.||..|..||..:
Zfish    73 IASEAGRGGRTVVYCKNGRSRSATVCVAYLMKHQSLTLTDAFQVVKSARSVVEPNPGFWSQLERY 137

  Fly   353 ESQLRL-RPGSRFS 365
            |.:|:: |.|||.|
Zfish   138 EQELKIRRSGSRKS 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSPc	215..353	CDD:238073	40/129 (31%)
		CDC14	<242..359	CDD:225297	37/117 (32%)
dusp28	XP_001344320.3	DSPc	3..138	CDD:238073	40/129 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940