DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sfxn2 and Sfxn2

DIOPT Version :9

Sequence 1:	NP_649086.2	Gene:	Sfxn2 / 40080	FlyBaseID:	FBgn0036843	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_444426.3	Gene:	Sfxn2 / 94279	MGIID:	2137678	Length:	322	Species:	Mus musculus

Alignment Length:	319	Identity:	184/319 - (57%)
Similarity:	234/319 - (73%)	Gaps:	5/319 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DVDKPLFDLSTFAGRFQYFAWMTDPRTVVVSSDRLLEAKAMVERYRKGDQSPPLKPEEVHYNMKL 73
            ::|.|.:|..||.||.::|..:||||||..|...|..|||:||:.|.|...|..:.|::.|..||
Mouse     9 NIDAPRWDQCTFLGRVKHFFNITDPRTVFASEQELDWAKAVVEKSRMGLVPPGTQMEQLLYAKKL 73

  Fly    74 YNSAFHPDTGELQNFCGRMSFQVPGGMLITGGMLAFYRTVPAVVLWQFINQSFNAVVNYTNRNAN 138
            |:|||||||||..|..|||||||||||||||.||.||||:|||:.||::||||||:||||||||.
Mouse    74 YDSAFHPDTGEKMNVIGRMSFQVPGGMLITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAA 138

  Fly   139 SPTSVTQLGVAYVSATTSALVAAIGCKNYWSKKATPLFQRFVPFAAVAAANFVNIPLMRQNEIIN 203
            |||||.|:.::|.:|||:|:..|:| .|.|:|:|.||..|:||||||||||.||||:|||.|:|.
Mouse   139 SPTSVRQMALSYFTATTTAVATAVG-MNMWTKRAPPLVGRWVPFAAVAAANCVNIPMMRQQELIQ 202

  Fly   204 GIEVKNDDGVVVGQSRLAAIKGIGEVVVSRIAMAAPGMLVLPLIMERLEKLPAYRRIKWINAPFQ 268
            ||.||:.:...:|.|:.||..||.:||:|||.||||||::||:||||||:|...:::|.::||.|
Mouse   203 GICVKDRNQNELGHSQRAAAVGIAQVVISRITMAAPGMILLPVIMERLERLHLMKKVKVMHAPLQ 267

  Fly   269 TLLVGCFLCFMVPTACALFPQQCSLDTSIMRTFEPELYEDLEKKTQGKVPKRVYFNKGL 327
            .||.||||.||||.||.||||:|.|..|.:   ||||.:.::.| .|:....|||||||
Mouse   268 VLLCGCFLLFMVPVACGLFPQECELSVSYL---EPELRDTIKAK-YGEQVLFVYFNKGL 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sfxn2	NP_649086.2	Mtc	15..327	CDD:309082	180/311 (58%)
Sfxn2	NP_444426.3	Mtc	15..322	CDD:281771	175/306 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830981
Domainoid	1	1.000	346	1.000	Domainoid score	I1048
eggNOG	1	0.900	-	-		E1_KOG3767
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14227
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2262
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53494
OrthoDB	1	1.010	-	-		D340335at33208
OrthoFinder	1	1.000	-	-		FOG0000786
OrthoInspector	1	1.000	-	-		oto92732
orthoMCL	1	0.900	-	-		OOG6_109681
Panther	1	1.100	-	-	LDO	PTHR11153
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3647
SonicParanoid	1	1.000	-	-		X842
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800