Protein Alignment Sfxn2 and SFXN5

DIOPT Version :10

• Sequence 1: NP_649086.2
• Gene: Sfxn2 / 40080
• FlyBaseID: FBgn0036843
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_001317329.1
• Gene: SFXN5 / 94097
• HGNCID: 16073
• Length: 357
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 109/286 - (38%)
• Similarity: 161/286 - (56%)
• Gaps: 10/286 - (3%)

  Fly    12 KPLFDLSTFAGRFQYFAWMTDPRTVVVSSDRLLEAKAMVERYRKGDQSPPLKPEEVHYNMKLYNS 76
            ||.|..::|.|||::|..:.||||:.|:..||.||..::|.|:.|...|.:..|::....|:..:
Human    29 KPRFQQTSFYGRFRHFLDIIDPRTLFVTERRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQA 93

  Fly    77 AFHPDTGELQNFCGRMSFQVPGGMLITGGMLAFYRTVPAVVLWQFINQSFNAVVNYTNRNANSPT 141
            ..||||.|......|||..:|.|..|..|:|...:|:.:.|.||::|||.||.|||.||||..|:
Human    94 ILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPS 158

  Fly   142 SVTQLGVAYVSATTSALVAAIGCKNYWSK--KATP----LFQRFVPFAAVAAANFVNIPLMRQNE 200
            ..::....|:.|..||:..|:|......|  |.||    |.||||||.|||:||..|:.|||..|
Human   159 PASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLIQRFVPFPAVASANICNVVLMRYGE 223

  Fly   201 IINGIEVKNDDGVVVGQSRLAAIKGIGEVVVSRIAMAAPGMLVLPLIMERLEKLPAYRRIKWINA 265
            :..||:|.:.||.:||.|::||...:.|..::|:.:..|.:::.|::|..|||....:....:..
Human   224 LEEGIDVLDSDGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLL 288

  Fly   266 PFQTLLVGCFLCF--MVPTACALFPQ 289
            |.|:|:  |...|  .:|.|.:||||
Human   289 PVQSLV--CLAAFGLALPLAISLFPQ 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfxn2	NP_649086.2	SFXNs	9..327	CDD:461063	109/286 (38%)
SFXN5	NP_001317329.1	SFXNs	26..315	CDD:461063	109/286 (38%)