DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sfxn2 and SPAC17G6.15c

DIOPT Version :9

Sequence 1:	NP_649086.2	Gene:	Sfxn2 / 40080	FlyBaseID:	FBgn0036843	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_594262.2	Gene:	SPAC17G6.15c / 2542199	PomBaseID:	SPAC17G6.15c	Length:	322	Species:	Schizosaccharomyces pombe

Alignment Length:	319	Identity:	102/319 - (31%)
Similarity:	162/319 - (50%)	Gaps:	13/319 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FDLSTFAGRFQYFAWMTDPRTVVVSSDRLLEAKAMVERYRKGDQSPPLKPEEVHYNMKLYNSAFH 79
            :||||:.||.::...:|||||::.:|..|..|...:|.|..|..:.  ..|.|.:..|:.:|..|
pombe    11 YDLSTYWGRVRHAMDITDPRTLLSTSQDLNSAVKTLEDYGAGKIAQ--LDETVWHAKKIVDSTLH 73

  Fly    80 PDTGELQNFCGRMSFQVPGGMLITGGMLAFYRTVPAVVLWQFINQSFNAVVNYTNRNANSPTSVT 144
            |||.|......|||..|...:::|.|||.........|.||::|||.|...|..|.|.::..::.
pombe    74 PDTKEPVFLPFRMSCFVLTNLVVTAGMLQPNLGTAGTVFWQWMNQSVNVAFNSANANKSTQLTLP 138

  Fly   145 QLGVAYVSATTSALVAAIGCK------NYWSKKATPLFQRFVPFAAVAAANFVNIPLMRQNEIIN 203
            |:..:|:.|.:::...|||..      |:.|..:..:..|..||||||:|..:|:.|||..|:..
pombe   139 QMTKSYIYAVSASCGVAIGLNKIVPRMNFLSSSSKAVLGRLTPFAAVASAGVLNVFLMRGEELRQ 203

  Fly   204 GIEVKNDDGVVVGQSRLAAIKGIGEVVVSRIAMAAPGMLVLPLIMERLEKLPAYRRIKWINAPFQ 268
            ||:|.:.:|..:|:|:.||...:||..:||:..|:|.|::.||::.||:|....|....:..|..
pombe   204 GIDVFDKEGESLGKSKKAAFYAVGETALSRVINASPIMVIPPLVLMRLQKQNWLRTRPKLTIPVN 268

  Fly   269 TLLVGCFLCFMVPTACALFPQQCSLDTSIMRTFEPELYEDLEKKTQGKVPKRVYFNKGL 327
            ..|:.......:|.|..:||.:..:...   ..||:.:...:|..|..|  .|.||:||
pombe   269 LGLITLTSLIALPLAIGVFPAREKISPF---KLEPQFHHLKDKSDQPIV--EVEFNRGL 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sfxn2	NP_649086.2	Mtc	15..327	CDD:309082	100/317 (32%)
SPAC17G6.15c	NP_594262.2	Mtc	11..322	CDD:281771	100/317 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	173	1.000	Domainoid score	I873
eggNOG	1	0.900	-	-		E1_KOG3767
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	175	1.000	Inparanoid score	I1162
OMA	1	1.010	-	-		QHG53494
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47124
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.830