Protein Alignment Ugt316A1 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001004271.1
• Gene: Ugt2b35 / 83808
• RGDID: 620895
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 118/547 - (21%)
• Similarity: 222/547 - (40%)
• Gaps: 99/547 - (18%)

  Fly    13 CGIVLGANVLTVFPSVWK---SHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIREL 74
            ||.||          ||.   ||::..:.:|:|||:.  .|.||::.|.|:   |..:..:..:|
  Rat    23 CGKVL----------VWPMEYSHWMNIKIILEELVQK--GHEVTVLRPSAS---VFLDPKETSDL 72

  Fly    75 RIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLI----------------------------YAG 111
            :       ::....||.:.::.     ..|||.:                            |..
  Rat    73 K-------FVTFPTSFSSHDLE-----NFFTRFVNVWTYELPRDTCLSYFLYLQDTIDEYSDYCL 125

  Fly   112 TTNVDILLSDPQVRKLLTSGEKFDLLIVDLF-----LSDALLGLAFYYGI---PTVAVSPTGANS 168
            |...:.:.:...:.||..|  |||::..|..     |...||.:.|.|.:   |...:     ..
  Rat   126 TVCKEAVSNKQFMTKLQES--KFDVVFSDAIGPCGELIAELLQIPFLYSLRFSPGYTI-----EK 183

  Fly   169 WLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLV 233
            ::..:...|   |..|..|.....:|...:|:.|.:.    .|.::|:....::..:...:...:
  Rat   184 YIGGVLFPP---SYVPMIFSGLAGQMTFIERVHNMIC----MLYFDFWFQTFREKKWDPFYSKTL 241

  Fly   234 KELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESA-PSG 297
            .......::.....:.||.|:..|.:|....||:..:||||......  |||.:..|::|: ..|
  Rat   242 GRPTTLAEIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCKPAKP--LPKDIEDFVQSSGEHG 304

  Fly   298 VIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQ--VLPENVMIADWWPQQ 360
            |:.||||:.|.  .:.:||..||......:.:   .:.|   .|..::  .|..|..:..|.||.
  Rat   305 VVVFSLGSMVR--NMTEEKANIIAWALAQIPQ---KVLW---RFDGKKPPTLGPNTRLYKWLPQN 361

  Fly   361 AILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSL 425
            .:|.||:.|.|::..|...::|:|....|::.||:..||......:...|.:|.|.:.:::...:
  Rat   362 DLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGAAVEVNFRTMSKSDM 426

  Fly   426 LHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEG 490
            |:.:.::..|..|.:....|......:.:.|:.:||..|:.::...||..|:|..:.|.:::...
  Rat   427 LNALEEVINNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHKGAKHLRSLGHNLPWYQYHS 491

  Fly   491 VDVL--LIIAVGFFGILTIPFLAICFI 515
            :||:  |:..|.    :|:.....||:
  Rat   492 LDVIGFLLTCVA----VTVVLALKCFL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	99/483 (20%)
Ugt2b35	NP_001004271.1	UDPGT	24..527	CDD:278624	117/546 (21%)