Protein Alignment Ugt316A1 and ugt2a6

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001138283.1
• Gene: ugt2a6 / 797211
• ZFINID: ZDB-GENE-081104-3
• Length: 529
• Species: Danio rerio
• Alignment Length: 552
• Identity: 142/552 - (25%)
• Similarity: 246/552 - (44%)
• Gaps: 91/552 - (16%)

  Fly    11 LLCGIVLG-ANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLI-------SPHAAQEGVDAE 67
            ||||:.:| :..:.|.|..: ||:...|.:::.||:.  |||||::       .||..:|..:..
Zfish    11 LLCGVDVGWSGRVLVMPGEY-SHWHNMRPVIEALVDK--NHSVTVLVGSSSPTVPHTQKERFEYH 72

  Fly    68 IPKI---RELRIEGL----RENWLDMGMSFEAEEMRAQSVMERF---TRLIYAGTTNVDILLSDP 122
            :.|:   :|: ::.|    .|.|::..:|...:.:....:|..|   :..:..|..:|.:|
Zfish    73 VFKVNMEKEV-VDYLWIHFHELWMNETISTYEKTLEVWQLMSLFRAHSEELVKGLFDVGLL---- 132

  Fly   123 QVRKLLTSGEKFDLLIVDLFL--SDALLGLAFYYGIPTVAVSPTGANSWLNNMFGN---PQSSSL 182
               |.|.. ..:|:|..||.:  ||.   :|....||.|........|.|..:.|.   |||
Zfish   133 ---KTLRD-SNYDVLFSDLTMPFSDL---MAQKLNIPHVLSMRISFASALERLCGQMPVPQS--- 187

  Fly   183 DPSNFLP-------FTERMNTRQRILNSLM-----STFERLT-YNFFHLISQQS-VYTNHFELLV 233
                ::|       .|:||:..:|:.|.|:     :.|:..| :.|.|:.::.| ..|...|.:.
Zfish   188 ----YVPAAVAQGHLTDRMSFTERVENMLLYITHTAMFQLTTKFTFDHIYAEISGEPTTMCETIG 248

  Fly   234 KELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESA-PSG 297
            |           ..:.||.::....|||.:.||...||||.......  |.|.|..|::|: ..|
Zfish   249 K-----------TDIWLIRTYWDFEYPRPFPPNFKFVGGLQCKPAKP--LAKELEEFVQSSGDHG 300

  Fly   298 VIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAI 362
            ::.||||:.::  .|..:|...|....|.:.:   .:.|.....|.|.:.| |..|.||.||..:
Zfish   301 IVVFSLGSMIK--NLTVQKANTIAAALGQISQ---KVVWRYSGKTPETLAP-NTKIYDWIPQNDL 359

  Fly   363 LHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLH 427
            |.||:.|.||:..|...::|:|....|::.:|:..:|......|:..|.:|.:.:.:|....|:.
Zfish   360 LGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFTLESKDLVD 424

  Fly   428 GIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVD 492
            .::.:..|.||.|.:.:|......:...|:.:||..|:.::.:.||..|:..|:.|::::...:|
Zfish   425 ALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLD 489

  Fly   493 V---LLIIAVGFFGILTIPFL---AICFILRK 518
            |   ||.|..      .|.||   |.||:.|:
Zfish   490 VAAFLLSITA------LITFLWVKACCFLFRR 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	117/478 (24%)
ugt2a6	NP_001138283.1	UDPGT	21..519	CDD:278624	137/542 (25%)