Protein Alignment Ugt316A1 and ugt5a2

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001070191.3
• Gene: ugt5a2 / 767756
• ZFINID: ZDB-GENE-061103-373
• Length: 524
• Species: Danio rerio
• Alignment Length: 583
• Identity: 133/583 - (22%)
• Similarity: 239/583 - (40%)
• Gaps: 131/583 - (22%)

  Fly     4 LQVFLGTLLCGIVLG---ANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLI---------- 55
            |.:||  |||  ||.   |..|.|.| |..||::..:.|:.||  .|..||:|::
Zfish     7 LGLFL--LLC--VLSRSYAGKLLVVP-VEGSHWVNMKVLIVEL--HSRGHSITVVRGSSSWYIEE 64

  Fly    56 -SPHAAQEGVD----------AEIPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIY 109
             ||......||          ..:|.:.:::.:| :..|.:|.::.|         |..|....:
Zfish    65 QSPLYTSITVDNGVFDDDFMETFLPHLLKIQRQG-KSFWNEMALADE---------MIHFVTETH 119

  Fly   110 AGTTNVDILLSDPQVRKLLTSGEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGAN-SWLNNM 173
            ..:.|:..:|.:.:..........:|:::.|......:| ||...|:|.|      .| .|  .:
Zfish   120 KQSCNMTAILFENETLMNSLKDAAYDVVLTDPAYGSGVL-LAHRLGLPLV------YNVRW--TV 175

  Fly   174 FGN------PQSSSLDPSNFLPFTERMNTRQRILNSLM-------------STFERLTYNFFHLI 219
            :|.      |...|..|.:.|..|::|...||::|.:.             |.::.||..:|
Zfish   176 YGEAHFDIAPSPLSYVPVSGLQLTDKMTFSQRVMNMMTYIMIRYKYSKNFGSPYQELTQKYF--- 237

  Fly   220 SQQSVYTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLP 284
               ....|.|.||           ::..|.|:.:.....:||..:||:|.:||........  ||
Zfish   238 ---GPNVNFFSLL-----------QDADLWLMRNDFTFEFPRPTMPNVVYMGGFQCKPAKP--LP 286

  Fly   285 KHLLSFMESA-PSGVIYFSLGA-------------DVETAQLPQEKLAIILDVFGHLKEFHFLLK 335
            ..|..|::|: ..|||..|||.             ....|||||:.:
Zfish   287 GDLEEFVQSSGEHGVIMMSLGTVFGQLLSELNDEIAAAFAQLPQKVI------------------ 333

  Fly   336 WEKEEFTAEQV--LPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAE 398
            |   .:|..:.  |..|.:|.:|.||..:|.||:.|:|::..|...:.|:|....|::.:|:..:
Zfish   334 W---RYTGPRPANLGNNTLIVNWLPQNDLLGHPKTKLFVAHGGTNGLQEAIYHGVPIVGLPLAFD 395

  Fly   399 QEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRK 463
            |.....|::..|.:..|.:.:|.....|..::::..|.||.|.:.:|.:....:...|:.:|:..
Zfish   396 QPDNLSRMRAKGTAKIVEFATLDRAVFLEALKEVLHNPSYRENMQKLSKLHHDQPMKPLDRAIFW 460

  Fly   464 IQLILESGGADFLKSHANTLNFWRAEGVDVL--LIIAVGFFGIL---TIPFLAICFILRKSYH 521
            |:.::.:.||..|::.:..:::...:.:||:  |::.|..|.:|   |:.:..:|...:|..|
Zfish   461 IEFVMRNKGAPHLRTQSFRMSWIEYQSIDVILTLMLMVLVFVLLTAYTMKYFCLCLFRKKVKH 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	110/498 (22%)
ugt5a2	NP_001070191.3	None