Protein Alignment Ugt316A1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_690024.1
• Gene: Ugt2b1 / 71773
• MGIID: 1919023
• Length: 529
• Species: Mus musculus
• Alignment Length: 555
• Identity: 123/555 - (22%)
• Similarity: 241/555 - (43%)
• Gaps: 115/555 - (20%)

  Fly    13 CGIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAA-------QEGVDAEI-- 68
            ||.||      |:|:.: ||::..:.:|.|||:.  .|.||::...|:       :..::.||
Mouse    23 CGKVL------VWPTEY-SHWINMKIILDELVQR--GHDVTVLISSASILIGPSNESSINFEIYS 78

  Fly    69 -PKIRELRIEGLRENWLDMGMSFEAEEM-------RAQSVMERFTRLIYAGTTNVDILLSDPQVR 125
             |..:: .:|...|.|:. ..::|.:::       :.|.:...::.:|.:....|  :.:...::
Mouse    79 APLSKD-DLEYAFEKWVG-NWTYELKKLPFWTSYSKLQKISSEYSDMIESFCKAV--VWNKSLMK 139

  Fly   126 KLLTSGEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLD------- 183
            ||  .|.|||:::.|                   |:.|.|  ..|:.:...|...||.
Mouse   140 KL--QGSKFDVVLAD-------------------ALVPCG--ELLSELLKTPLVYSLRFCPGYKC 181

  Fly   184 ---------PSNFLP-----FTERMNTRQRILNSL--------MSTFERLTYNFFH--LISQQSV 224
                     |.:::|     .::.|...:|:.|.|        ..||...::|.|:  ::.:.:.
Mouse   182 EKYSGGLPLPPSYVPVVLSELSDHMTFAERVKNMLQVLLFDFWFQTFNEKSWNQFYSDVLGRPTT 246

  Fly   225 YTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLS 289
            .|   |::.|           ..:.|:.:...|.:|..:|||...|||||......  |||.:..
Mouse   247 LT---EMMGK-----------ADIWLVRTFWDLKFPHPFLPNFDFVGGLHCKPAKP--LPKEMEE 295

  Fly   290 FMESA-PSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMI 353
            |::|: ..||:.||||:.|:  .:.:||..::......:.: ..|.:::.::   ...|..|..:
Mouse   296 FVQSSGEHGVVVFSLGSMVK--NIKEEKANVVASALAQIPQ-KVLWRFDGKK---PDTLGSNTRL 354

  Fly   354 ADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYD 418
            ..|.||..:|.||:.|.||:..|...::|:|....|::.||:..:|......:...|.:|.|.:|
Mouse   355 YKWIPQNDLLGHPKTKAFIAHGGTNGIYEAIYHGIPIVGIPLFGDQPDNINHIVAKGAAVRVDFD 419

  Fly   419 SLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTL 483
            :::...||..::.:..:.||.|...:|......:...|:.:||..|:.::.:.||..|:...:.|
Mouse   420 TMSTTDLLTALKTVINDPSYKENAMRLSRIHHDQPMKPLDRAVFWIEYVMRNKGAKHLRPALHDL 484

  Fly   484 NFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRK 518
            .:::...:||:        |.|.:..:|:.||:.|
Mouse   485 TWFQYHSLDVI--------GFLLVCVVAVVFIIAK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	104/490 (21%)
Ugt2b1	NP_690024.1	UDPGT	24..527	CDD:278624	122/554 (22%)