Protein Alignment Ugt316A1 and ugt2a2

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001018306.2
• Gene: ugt2a2 / 553952
• ZFINID: ZDB-GENE-080721-21
• Length: 534
• Species: Danio rerio
• Alignment Length: 528
• Identity: 143/528 - (27%)
• Similarity: 243/528 - (46%)
• Gaps: 63/528 - (11%)

  Fly    20 NVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLI----SP---HAAQEGVD---AEIPKIREL 74
            ||| |.|..: ||:...|.::.||:  :.||:||::    ||   ...||...   .|:| :...
Zfish    24 NVL-VLPGEY-SHWQNMRNVVDELL--NRNHTVTVLVCSASPTINFTQQERFQYLVFEVP-LSAQ 83

  Fly    75 RIEGLRENWLDMGMSFEAEE--MRAQSVMERFTRLIYAGTTNVDILL-SDPQVRKLLTSGEKFDL 136
            .::|..|..:.:.....:..  ..|..::|...|:........|.:| :|..:.:|  |..|||:
Zfish    84 ELDGASEELIHIWTQHPSPNRLQTALQIIELLGRVRVMHRAMCDSMLRNDALIAQL--SALKFDV 146

  Fly   137 LIVD-LFLSDALLGLAFYYGIP---TVAVSPTGANSWLNNMFGNPQSSSLDPSNFLP-----FTE 192
            |..| :|:...|  ||...|:|   :|.:||   ...|..|.|...:    |.:|:|     .|:
Zfish   147 LFNDPMFMCADL--LAEMLGLPLVLSVRISP---GFCLERMCGQMPA----PPSFVPITQTVLTD 202

  Fly   193 RMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLTKNLSLALINSHPGL 257
            ||...:|:.|.:.:....:::.....||..|.||   ::|.|...:...:.| ..:.||.::...
Zfish   203 RMCFMERVQNMIANIVFSVSFYIVAWISLDSYYT---DVLGKPTTMCETMGK-ADIWLIRTYWDF 263

  Fly   258 HYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESA-PSGVIYFSLGADVETAQLPQEKLAIIL 321
            .|||.:.||...|||||......  |.|.:..|::|: ..||:.||||:.::  .|..|:...|.
Zfish   264 EYPRPFPPNFKFVGGLHCKPAKP--LSKEMEEFVQSSGDHGVVVFSLGSMIK--NLTSERANTIA 324

  Fly   322 DVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISG 386
            ...|.:.:   .:.|.....|.|.:.| |..|.||.||..:|.||:.|.||:..|...::|:|..
Zfish   325 AALGQIPQ---KVVWRYSGKTPETLAP-NTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYH 385

  Fly   387 QKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLIS 451
            ..|::.:|:.|:|......::..|.:|.:..::|....|:..::.:..|.||.|.:.:|......
Zfish   386 GVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHD 450

  Fly   452 RDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDV---LLIIAVGFFGILTIPFL--- 510
            :...|:.:||..|:.::.:.||..|:..|:.|::::...:||   ||.||.      .|.||
Zfish   451 QPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAA------LITFLWVK 509

  Fly   511 AICFILRK 518
            |.||:.|:
Zfish   510 ACCFLFRR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	122/463 (26%)
ugt2a2	NP_001018306.2	UDPGT	23..521	CDD:278624	143/528 (27%)