Protein Alignment Ugt316A1 and Ugt2a2

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 554
• Identity: 152/554 - (27%)
• Similarity: 254/554 - (45%)
• Gaps: 77/554 - (13%)

  Fly     2 QILQVFLGTL-LCGIVLGANVLTVFPSVWK---SHYLFGRRLLQELVESSGNHSVTLISPHAA-- 60
            ::||:.:..| |..|||..||:     ||.   ||:|..:.||:|||:.  |||||:::|...
Mouse     4 KVLQLLIFHLTLAEIVLSGNVV-----VWPTDGSHWLNIKILLEELVQR--NHSVTVLAPSETLF 61

  Fly    61 -QEGVDA-----EIP------KIRELRIEGLRENWLD-----MGM-SFEAEEMRAQSVMERFTRL 107
             ...:||     |||      ||.|: ||.:...|||     :.| :|..|       :......
Mouse    62 INSRLDAFINFEEIPVSYTKSKIDEI-IEHMIALWLDHRPTPLTMWTFYKE-------LGNLLAT 118

  Fly   108 IYAGTTN---VDILLSDPQVRKLLTSGEKFDLLIVDLF-----LSDALLGLAFYYGIPTVAVSPT 164
            .|  |||   .|.:|::|.|.:.|..| .||:|:.|..     |....||:.|.|   |:..||.
Mouse   119 FY--TTNKQMCDGVLNNPTVMERLQKG-GFDVLLADPVTMCGELVALKLGIPFVY---TLRFSPA 177

  Fly   165 GANSWLNNMFGN-PQSSSLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNH 228
            ..   :....|. |...|..|:.....|::|:..:|:.|.:  ::....|.|.....:.:.|  :
Mouse   178 FT---VERHCGKIPAPISYVPAALSELTDQMSFGERVKNII--SYSLQDYIFKTYWGEWNSY--Y 235

  Fly   229 FELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFME- 292
            .::|.:...|...:.| ..:.|:.::....:||.||||...|||||......  |||.:..|::
Mouse   236 SKVLGRPTTLCETMGK-AEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKP--LPKEMEEFVQT 297

  Fly   293 SAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWW 357
            |...|::.||||:.|:  .|..||..:|......:.:   .:.| :.:......|..|..:.||.
Mouse   298 SGEHGIVVFSLGSMVK--NLTDEKANLIASALAQIPQ---KVLW-RYKGKIPDTLGSNTRLFDWI 356

  Fly   358 PQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAY 422
            ||..:|.||:.:.||:..|...::|:|....|::.:|:.|:|......::..|.:|.|..:::..
Mouse   357 PQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTS 421

  Fly   423 DSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWR 487
            ..||:.:|.:....||.|...:|......:...|:.:||..|:.::...||..|:..|:.|::::
Mouse   422 SDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQ 486

  Fly   488 AEGVDVL-LIIAVGFFGILTIPFLAIC--FILRK 518
            ...:||: .::|.....||.:   |.|  ||.:|
Mouse   487 YHSLDVIGFLLACVASAILLV---AKCCLFIFQK 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	127/474 (27%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	144/533 (27%)