Protein Alignment Ugt316A1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 563
• Identity: 144/563 - (25%)
• Similarity: 255/563 - (45%)
• Gaps: 85/563 - (15%)

  Fly     4 LQVFLG-TLLCGI--VLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVD 65
            ||..:| .|||.:  ..|..|| ||| |..||:|..|.:::||  .:..|...:::|.......:
Mouse     7 LQGLVGLLLLCALPWTEGEKVL-VFP-VGGSHWLSMRDVVREL--HAQGHQTVVLAPEVNMRIKE 67

  Fly    66 AE--------IPKIRELRIEGLREN---WLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILL 119
            .:        :|..|: .:|.:.||   :.|.| ::..:..:....:...:.::....||  ||.
Mouse    68 EDFFTFKVYAVPYTRQ-ELEEMMENLKVFFDTG-NYMKKIFKTSEALRNMSTVLLKTCTN--ILH 128

  Fly   120 SDPQVRKLLTSGEKFDLLIVD-LFLSDALLGLAFYYGIPTV---AVSPTGANSWLNNMFGNPQSS 180
            ::..:..|.:|  .||::..| :|...||  ||.|.|||.|   ...|.|........   |..|
Mouse   129 NESLLHHLNSS--SFDVVFTDPVFPCGAL--LAKYLGIPAVFFLRYIPCGIEYEATQC---PSPS 186

  Fly   181 SLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNH-----FELLVKELPLYR 240
            |..|:.|...::.|:..||:.|.|           :||:.:   |..|     :|.|..|| ..|
Mouse   187 SYIPNLFTRLSDHMDFLQRVQNML-----------YHLVLK---YICHLLITPYESLASEL-FQR 236

  Fly   241 -----DLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFME-SAPSGVI 299
                 :|....|:.|......|.|||..:||||.:||::.  :....|.:...:::. |...|::
Mouse   237 EVSSVELFSYASVWLFRGDFVLDYPRPIMPNMVFIGGINC--VTKKPLSQEFEAYVNASGEHGIV 299

  Fly   300 YFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILH 364
            .||||:.|  :::|::|...|.:..|.:.:   .:.| :...|....|.:|.::..|.||..:|.
Mouse   300 VFSLGSMV--SEIPEKKAMEIAEALGRIPQ---TVLW-RYTGTRPSNLAKNTILVKWLPQNDLLG 358

  Fly   365 HPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGI 429
            ||:.:.||:..|...::|.|....|::.:|:..:|...|||::..|..||:....:..|.|.:.:
Mouse   359 HPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENAL 423

  Fly   430 RQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVL 494
            :.:..|.||.|.:.:|......|...|:..||..::.::...||..|:..|:.|.:::...:||:
Mouse   424 KTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVI 488

  Fly   495 -LIIAVGFFGILTIPFLAI---------CF----ILRKSYHSQ 523
             .::|:    :||:.|:..         ||    .::||:.|:
Mouse   489 GFLLAI----VLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	119/467 (25%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	134/535 (25%)