Protein Alignment Ugt316A1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_787040.2
• Gene: Ugt1a8 / 301595
• RGDID: 708474
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 121/504 - (24%)
• Similarity: 224/504 - (44%)
• Gaps: 48/504 - (9%)

  Fly    31 SHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIRELRIEGLRENW----LDMGMSFE 91
            ||:...:.::::|  |...|.|.::.|.     |...:.|.....::....::    |:....|.
  Rat    36 SHWFTMQMIVEKL--SHRGHEVVVVIPE-----VSWHMGKSLNFTVKTYSVSYTLEDLNYHFKFF 93

  Fly    92 AEEMRAQSVMERFTRLIYAGTTNVDILLS-------DPQVRKLLTSGEKFDLLIVDLFLSDALLG 149
            |........:..|:.|.::|....::|.|       |.::.:.|.. ..||.:.:|.|....|:
  Rat    94 AHNQWKTQEVGMFSLLKHSGKGFFELLFSHCRSLFKDKKLVEYLKQ-SSFDAVFLDPFDVCGLI- 156

  Fly   150 LAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLMSTFERLTYN 214
            ||.|:.:|:|..|......:|:.....|...|..|.....||:.|..::|:.|.|....||....
  Rat   157 LAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFTDTMTFKERVWNHLSYMKERAFCP 221

  Fly   215 FFHLISQQSVYTNHFELL--VKELPL-YRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLS 276
            :|        :....|:.  |.:.|: .|||...:|:.:..:...|.:||..:||||.:||::..
  Rat   222 YF--------FKTAVEIASEVLQTPVTMRDLFSPVSIWMFRTDFVLEFPRPVMPNMVYIGGINCH 278

  Fly   277 HLNDDNLPKHLLSFME-SAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEE 340
              ....|.|...:::. |...|::.||||:.|  :::|::|...|.:..|.:.:   .:.| :..
  Rat   279 --QGKPLSKEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQ---TVLW-RYT 335

  Fly   341 FTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKR 405
            .|....|.:|.::..|.||..:|.||:.:.||:..|...::|.|....|::.:|:..:|...|||
  Rat   336 GTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKR 400

  Fly   406 LQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILES 470
            ::..|..||:....:..|.|.:.::.:..|.||.|.:.:|......|...|:..||..::.::..
  Rat   401 METRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRH 465

  Fly   471 GGADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRKS 519
            .||..|:..|:.|.:::...:||:        |.|....|.:.||:.||
  Rat   466 KGAPHLRPAAHDLTWYQYHSLDVI--------GFLLAIVLTVVFIVYKS 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	105/444 (24%)
Ugt1a8	NP_787040.2	UDPGT	26..521	CDD:278624	121/504 (24%)