Protein Alignment Ugt316A1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 129/547 - (23%)
• Similarity: 232/547 - (42%)
• Gaps: 97/547 - (17%)

  Fly    13 CGIVLGANVLTVFPSVW---KSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIREL 74
            |||.  :.||     ||   .||:|..:.:|:||  ::..|.||::.    ...:..:..|:..|
  Rat    20 CGIC--SKVL-----VWPCDMSHWLNLKTILEEL--AARGHEVTVLK----YPSIIIDQSKLTPL 71

  Fly    75 RIEGL--------RENWLDMGMSFEAEEM-------RAQSVMERFTRLIYAGTTNVDILLSDPQV 124
            :.|.:        .||.|:..::.....:       .|:::.:.|.:|    |.|.:.|......
  Rat    72 QFENIPVLYETEVAENHLNEIVNLAVNVIPNLSLWEAARTLQDFFLQL----TGNFEDLCRSTLY 132

  Fly   125 RKLLTS---GEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLD--- 183
            .:.|.:   ..|:|::::|..:....| :|....||.|            |........|::
  Rat   133 NQTLMNKLRDAKYDVMVLDPVIPCGEL-VAEVLQIPFV------------NTLRFSMGYSMEKYC 184

  Fly   184 -----PSNFLP-----FTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPL 238
                 |.:::|     .|:.|...:|:.|.::|.       ||....||..:....:...|.|..
  Rat   185 GQLPVPLSYVPVVMGELTDHMTFTERVKNMMLSL-------FFEFWLQQYDFAFWDQFYSKTLGR 242

  Fly   239 YRDLTKNLSLA---LINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESA-PSGVI 299
            .....|.:..|   ||.::..:.:||.||||...|||||......  |||.|..|::|: ..||:
  Rat   243 PTTFCKTVGKAEIWLIRTYWDIEFPRPYLPNFEFVGGLHCKPAKP--LPKELEEFVQSSGEHGVV 305

  Fly   300 YFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWE---KEEFTAEQVLPENVMIADWWPQQA 361
            .||||:.::  .|.:||..:|......:.:   .:.|.   |:..|    |..|..|.:|.||..
  Rat   306 VFSLGSMIK--NLTEEKANLIASALAQIPQ---KVLWRYSGKKPAT----LGPNTRILNWIPQND 361

  Fly   362 ILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLL 426
            :|.||:.:.||:..|...::|:|....|::.||:..:|......::..|.:|.|..:::....||
  Rat   362 LLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADLL 426

  Fly   427 HGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGV 491
            ..:|.:....||.|...:|......:...|:.:||..|:.::...||..|:..|:.|::::...:
  Rat   427 SALRAVINEPSYKENAMRLSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSL 491

  Fly   492 DVLLIIAVGFFGILTIPFLAICFILRK 518
            ||:        |.|.:..:.:.|::.|
  Rat   492 DVI--------GFLLVCVVTLTFVITK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	112/482 (23%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	126/540 (23%)