Protein Alignment Ugt316A1 and Ugt2b7

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_775445.2
• Gene: Ugt2b7 / 286989
• RGDID: 708417
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 136/561 - (24%)
• Similarity: 228/561 - (40%)
• Gaps: 116/561 - (20%)

  Fly    13 CGIVLGANVLTVFPSVWK---SHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIREL 74
            ||.||          ||.   ||::..:.:|.|||:.  .|.||::.| ::...:|   ||
  Rat    23 CGKVL----------VWPLEYSHWMNLKIILDELVQR--GHEVTVLRP-SSSVFLD---PK---- 67

  Fly    75 RIEGL-RENWLDMGMSFEAEEMRAQSV------MERFTRLIYAGTTNVDILLSDPQVRKLLTSGE 132
            :..|| .|.:.....:.|.|:...|.|      :.::|.|.|.           |.:.|:.  |:
  Rat    68 KASGLVYETFPTTSNNDEVEKFFTQWVNTWTYDVPKYTCLRYY-----------PSLNKMF--GQ 119

  Fly   133 KFDLLI--------------------VDLFLSDA----------LLGLAFY--------YGIPTV 159
            ..||.:                    .|:.||||          :|.|.|.        |||...
  Rat   120 FSDLWLQLCREVVSNKHLMAKLKESQFDVVLSDAVGPCGELIAEILQLPFVYSLRFGIGYGIEKY 184

  Fly   160 AVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSV 224
            :.             |.|...|..|......:.:|...:|:.|.|...:....:..|........
  Rat   185 SA-------------GQPFPPSYVPIILSGLSGQMTFMERVENMLCLLYFDFWFESFPAKDWDPF 236

  Fly   225 YTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLS 289
            ::   |:|.:...:. |..|...:.||.|:..|.:||..|||:..|||||......  |||.:..
  Rat   237 FS---EILGRPTTMV-DTMKKAEIWLIRSYWDLEFPRPSLPNIEFVGGLHCQPAKP--LPKEMED 295

  Fly   290 FMESA-PSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMI 353
            |.:|: ..||:.||||:.:.  .:.||:...|......:.:..|   |..|....:.:.| |..:
  Rat   296 FAQSSGEHGVVVFSLGSMIR--NITQERANTIASALAQIPQKVF---WRFEGKKPDTLGP-NTRV 354

  Fly   354 ADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYD 418
            ..|.||..:|.||:.|.|::..|...::|||....|::.||:.|||......:...|.:|::.:.
  Rat   355 FKWIPQNDLLGHPKTKAFVTHGGANGIYESIHHGIPMVGIPLFAEQRDNVAHMVAKGAAVSLDFH 419

  Fly   419 SLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTL 483
            :::...||:.::.:....||.:|:..|......:...|:.:||..|:.::...||..|:..|:.|
  Rat   420 TMSSSDLLNALKAVINKPSYKKKVMWLSAIHHDQPLKPLDRAVFWIEFVMRHKGAKHLRPLAHNL 484

  Fly   484 NFWRAEGVDVLLIIAVGFF--GILTIPFLAI--CFILRKSY 520
            .:::...:||     :||.  .:|.|..||:  |..|.:.:
  Rat   485 AWYQYHSLDV-----IGFLLACVLAIVLLAVKCCLFLYRFF 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	114/490 (23%)
Ugt2b7	NP_775445.2	UDPGT	24..527	CDD:278624	135/560 (24%)