Protein Alignment Ugt316A1 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_766469.1
• Gene: Ugt2b35 / 243085
• MGIID: 3576100
• Length: 529
• Species: Mus musculus
• Alignment Length: 555
• Identity: 133/555 - (23%)
• Similarity: 227/555 - (40%)
• Gaps: 127/555 - (22%)

  Fly    13 CGIVLGANVLTVFPSVWK---SHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIRE- 73
            ||.||          ||.   ||::..:.:|.|||:.  .|.||::.| :|...||   ||...
Mouse    23 CGKVL----------VWPLEFSHWMNLKIILDELVQR--GHEVTVLRP-SASIFVD---PKYSPG 71

  Fly    74 LRIE----GLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQV---------R 125
            |:.|    ...:::|:..::...:|...:  :.|.|.|.|:....:...|||..:         :
Mouse    72 LKFETFPTAFSKDYLETFLTKLVDEWTFE--VPRDTCLSYSLLQTLFGKLSDYSLSLCKEAVSNK 134

  Fly   126 KLLTSGE--KFDLLIVDLFLS-----DALLGLAFYYGI---PTVAVSPTGANSWLNNMFGNPQSS 180
            :|:|..:  |||:||:|...|     ..||.:.|.|.:   |...|........|
Mouse   135 QLMTKFQESKFDVLILDAMASCGELIAQLLQIPFLYSLRFSPGYQVEKNSGGFVL---------- 189

  Fly   181 SLDPSNFLP-----------FTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVK 234
               |.:::|           ||||:   :.::..|...|      :|...:::.....:.|.|.:
Mouse   190 ---PPSYVPVILSGLGGQMTFTERV---KNMICMLYFDF------WFQTFTEKEWDQFYSETLGR 242

  Fly   235 ELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESA-PSGV 298
            ...|...:.| ..:..|.|:..|.:|...|||:..|||||......  |||.:..|::|: ..||
Mouse   243 PTTLIETMGK-AEMWFIRSYWDLEFPHPTLPNVEYVGGLHCKPAKP--LPKEMEDFVQSSGVHGV 304

  Fly   299 IYFSLGADVET-------------AQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPEN 350
            :.||||:.|..             ||:||:.|                  |..:..|...:.| |
Mouse   305 VVFSLGSMVSNMTEERANAISWALAQIPQKVL------------------WRFDGKTPASLGP-N 350

  Fly   351 VMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTV 415
            ..|..|.||..:|.||:.|.|::..|...::|:|....|::.||:.:||......:...|.:|.:
Mouse   351 TRIYKWLPQNDLLGHPKTKAFVTHGGANGLYEAIHHGIPMIGIPLFSEQHDNIAHMVAKGTAVAL 415

  Fly   416 GYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHA 480
            ...:::...||:.:.::..|.||.|.:..|......:...|:.:.:..|:.::...||..|:..|
Mouse   416 NIRTMSRSDLLNALEEVINNPSYKENVMWLSTIHHDQPMKPLNRTIFWIEFVMRHKGAKHLRPLA 480

  Fly   481 NTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFI 515
            :.|.:::...:||             |.||.:|.:
Mouse   481 HNLTWYQYHSLDV-------------IGFLLVCVV 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	117/493 (24%)
Ugt2b35	NP_766469.1	UDPGT	24..525	CDD:278624	132/554 (24%)