Protein Alignment Ugt316A1 and Ugt2b5

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_033493.3
• Gene: Ugt2b5 / 22238
• MGIID: 98900
• Length: 530
• Species: Mus musculus
• Alignment Length: 565
• Identity: 128/565 - (22%)
• Similarity: 221/565 - (39%)
• Gaps: 129/565 - (22%)

  Fly    13 CGIVLGANVLTVFPSVWK---SHYLFGRRLLQELVESSGNHSVTLISPHA--------------- 59
            ||.||          ||.   ||::..:.:|.|||:.  .|.||::.|.|
Mouse    23 CGKVL----------VWPMEFSHWMNIKIILDELVQR--GHEVTVLRPSAYYVLDPKKSPGLKFE 75

  Fly    60 ------AQEGVD-----------AEIPKIRELRIEGLRENWLDMGMSFEAEEMR-AQSVMERFTR 106
                  :::.::           .|:|:...|....|.:|.:|....:.....: ..|..|..|:
Mouse    76 TFPTSVSKDNLENFFIKFVDVWTYEMPRDTCLSYSPLLQNMIDEFSDYFLSLCKDVVSNKELMTK 140

  Fly   107 LIYAGTTNVDILLSDPQVRKLLTSGEKFDLLIVDLFLSDALLGLAFYYGI---PTVAVSPTGANS 168
            |   ..:..|:|||||    :.:.||    ||.:      ||.:.|.|.|   |...:..:....
Mouse   141 L---QESKFDVLLSDP----VASCGE----LIAE------LLQIPFLYSIRFSPGYQIEKSSGRF 188

  Fly   169 WLNNMFGNPQSSSLDPSNFLP-----FTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNH 228
            .|             |.:::|     ...:|...:||.|.:...:....:..|:.....|.|:
Mouse   189 LL-------------PPSYVPVILSGLGGQMTFIERIKNMICMLYFDFWFQMFNDKKWDSFYS-- 238

  Fly   229 FELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMES 293
             |.|.:...|...:.: ..:.||.|:..|.:|...|||:..|||||......  |||.:..|::|
Mouse   239 -EYLGRPTTLVETMGQ-AEMWLIRSNWDLEFPHPTLPNVDYVGGLHCKPAKP--LPKDMEEFVQS 299

  Fly   294 A-PSGVIYFSLGADVET-------------AQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAE 344
            : ..||:.||||:.|..             ||:||:.|                  | |.:....
Mouse   300 SGDHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQKVL------------------W-KFDGKTP 345

  Fly   345 QVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRH 409
            ..|..|..:..|.||..:|.||:.|.|::..|...|:|:|....|::.||:..||......:...
Mouse   346 ATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPLFGEQHDNIAHMVAK 410

  Fly   410 GVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGAD 474
            |.:|.:...:::...:|:.:.::..|..|.:....|......:...|:.:||..|:.::....|.
Mouse   411 GAAVALNIRTMSKSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWIEFVMRHKRAK 475

  Fly   475 FLKSHANTLNFWRAEGVDVL--LIIAVGFFGILTIPFLAICFILR 517
            .|:...:.|.:::...:||:  |:..|....:|::.  .:.||.|
Mouse   476 HLRPLGHNLTWYQYHSLDVIGFLLSCVATTIVLSVK--CLLFIYR 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	110/499 (22%)
Ugt2b5	NP_033493.3	UDPGT	24..527	CDD:278624	127/564 (23%)