Protein Alignment Ugt316A1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 563
• Identity: 138/563 - (24%)
• Similarity: 253/563 - (44%)
• Gaps: 99/563 - (17%)

  Fly    11 LLCGI--VLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQ-EGVD------A 66
            |||.:  ..||.|| |.| :..|.:|..|.:::|| .:.|:.:|.|.|..... :|.|      .
Mouse    18 LLCALPWAEGAKVL-VLP-MEGSQWLSMRDVVREL-HARGHQTVVLASEVTVHIKGEDFFTLKTY 79

  Fly    67 EIPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNV----DI-------LLS 120
            ..|..:|   |..:|...|:..:|:.         :.|.:..:..|.::    |:       ||.
Mouse    80 AFPYTKE---EYQQEILSDIEKTFKT---------QHFVKAFFETTASIRNFFDLYSNSCIALLH 132

  Fly   121 DPQVRKLLTSGEKFDLLIVD-LFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDP 184
            :..:.:.|.| ..||:::.| :|...|:  ||.|..||.|.:..:     |:.......:...:|
Mouse   133 NKMLIQQLNS-SFFDVILTDPIFPCGAV--LAKYLQIPAVFILRS-----LSCGIEYEATQCPNP 189

  Fly   185 SNFLP-----FTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLTK 244
            |:::|     .::.|:..||:.|.|.       |.....|.:.|:  ..:|.|..||     |.:
Mouse   190 SSYIPNLLTRLSDHMDFLQRVQNMLY-------YLVLKYICRLSI--TPYESLASEL-----LQR 240

  Fly   245 NLSLALINSHPG---------LHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFME-SAPSGVI 299
            .:||..:.||..         |.|||..:||||.:||::.  :....|.:...:::. |...|::
Mouse   241 EVSLVEVLSHASVWLFRGDFVLDYPRPIMPNMVFIGGINC--VTKKPLSQEFEAYVNASGEHGIV 303

  Fly   300 YFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILH 364
            .||||:.|  :::|::|...|.:..|.:.:   .:.| :...|....|.:|.::..|.||..:|.
Mouse   304 VFSLGSMV--SEIPEKKAMEIAEALGRIPQ---TVLW-RYTGTRPSNLAKNTILVKWLPQNDLLG 362

  Fly   365 HPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGI 429
            ||:.:.||:..|...::|.|....|::.:|:..:|...|||::..|..||:....:..|.|.:.:
Mouse   363 HPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENAL 427

  Fly   430 RQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVL 494
            :.:..|.||.|.:.:|......|...|:..||..::.::...||..|:..|:.|.:::...:||:
Mouse   428 KTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVI 492

  Fly   495 -LIIAVGFFGILTIPFLAI---------CF----ILRKSYHSQ 523
             .::|:    :||:.|:..         ||    .::||:.|:
Mouse   493 GFLLAI----VLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	116/475 (24%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	131/544 (24%)