Protein Alignment Ugt316A1 and Ugt2b38

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_598655.1
• Gene: Ugt2b38 / 100559
• MGIID: 2140794
• Length: 530
• Species: Mus musculus
• Alignment Length: 566
• Identity: 131/566 - (23%)
• Similarity: 226/566 - (39%)
• Gaps: 131/566 - (23%)

  Fly    13 CGIVLGANVLTVFPSVWK---SHYLFGRRLLQELVESSGNHSVTLISPHA--------------- 59
            ||.||          ||.   ||::..:.:|.|||:.  .|.||::.|.|
Mouse    23 CGKVL----------VWPMEFSHWMNIKIILDELVQR--GHEVTVLRPSAYYVLDPKKSPGLKFE 75

  Fly    60 ------AQEGVD-----------AEIPKIRELRIEGLRENWLDMGMSFEAEEMR-AQSVMERFTR 106
                  :::.::           .|:|:...|....|.:|.:|....:.....: ..|..|..|:
Mouse    76 TFPTSVSKDNLENFFIKFVDVWTYEMPRDTCLSYSPLLQNMIDEFSDYFLSLCKDVVSNKELMTK 140

  Fly   107 LIYAGTTNVDILLSDPQVRKLLTSGEKFDLLIVDLFLSDALLGLAFYYGI---PTVAVSPTGANS 168
            |   ..:..|:|||||    :.:.||    ||.:      ||.:.|.|.|   |...:..:....
Mouse   141 L---QESKFDVLLSDP----VASCGE----LIAE------LLQIPFLYSIRFSPGYQIEKSSGRF 188

  Fly   169 WLNNMFGNPQSSSLDPSNFLP-----FTERMNTRQRILNSLMSTFERLTYNF-FHLISQQSVYTN 227
            .|             |.:::|     ...:|...:|:.|.:.    ||.::| |.:.:.:...:.
Mouse   189 LL-------------PPSYVPVILSGLGGQMTFIERVKNMIC----RLYFDFWFQMFNDKKWDSF 236

  Fly   228 HFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFME 292
            :.|.|.:...|...:.| ..:.||.|:..|.:|...|||:..|||||......  |||.:..|::
Mouse   237 YSEYLGRPTTLAETMGK-AEMWLIRSNWDLEFPHPTLPNVDYVGGLHCKPAKP--LPKDMEEFVQ 298

  Fly   293 SA-PSGVIYFSLGADVET-------------AQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTA 343
            |: ..||:.||||:.|..             ||:||:.|                  | |.:...
Mouse   299 SSGDHGVVVFSLGSMVSNMTEEKANTIAWALAQIPQKVL------------------W-KFDGKT 344

  Fly   344 EQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQR 408
            ...|..|..:..|.||..:|.||:.|.|::..|...|:|.|....|::.||:..||......:..
Mouse   345 PATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEVIYHGIPMIGIPLFGEQHDNIAHMVA 409

  Fly   409 HGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGA 473
            .|.:||:...:::...:|:.:.::..|..|.:....|......:.:.|:.:||..::.::....|
Mouse   410 KGAAVTLNIRTMSRSDVLNALEEVIDNPFYKKNAIWLSTIHHDQPTKPLDRAVFWVEFVMRHKRA 474

  Fly   474 DFLKSHANTLNFWRAEGVDVL--LIIAVGFFGILTIPFLAICFILR 517
            ..|:|..:.|.:.:...:||:  |:..|....:||:.  .:.||.|
Mouse   475 KHLRSLGHNLTWHQYHFLDVIGFLLSCVAVTIVLTVK--CLLFIYR 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	112/500 (22%)
Ugt2b38	NP_598655.1	UDPGT	24..526	CDD:278624	130/565 (23%)