Protein Alignment Ugt316A1 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 549
• Identity: 141/549 - (25%)
• Similarity: 252/549 - (45%)
• Gaps: 81/549 - (14%)

  Fly     6 VFLGTLLCGIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAE--- 67
            :|||.:.   ::.|..|...| :..||:| ..|:|.|.:...|| .|.:::||:......:|
 Frog    18 LFLGRVQ---LIEAEKLLAIP-LDGSHWL-SMRILVESLGQRGN-QVVVLAPHSNIHIHPSENYI 76

  Fly    68 -----IPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNV-DILLSDPQVRK 126
                 :|..:||..|.:.::..|:        ...:.::::.|.: |...||| .|:.|..|  .
 Frog    77 LRTYPVPYSKELLKEQMVKSANDV--------FTKRPLLDKITNM-YQRITNVTGIVFSACQ--H 130

  Fly   127 LLTSGE--------KFDLLIVDLFLSDALLGLAFYYGIPTVAV---SPTGANSWLNNMFGNPQSS 180
            ||.|.|        .||..::|.|....:: :|.|..:|:|.:   .|.|.:......   |...
 Frog   131 LLHSKEIMQELQESAFDAALIDPFFPCGMI-VAEYLHLPSVYLLYGLPCGIDRLATQC---PSPL 191

  Fly   181 SLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLT-- 243
            |..|.:|...|:.|:..||:.|:|:...:....|..:     |.|..    |..|. |:|::|
 Frog   192 SYVPRHFTGNTDHMSFPQRLKNALLWPVDTFLCNLLY-----SPYAQ----LASEF-LHREMTIL 246

  Fly   244 ---KNLSLALINSHPGLHYPRAYLPNMVEVGGLHL---SHLNDDNLPKHLLSFMESAPSGVIYFS 302
               ...|:.|:.:.....|||..:||||.|||::.   .|||.:.  :.|::  .|...|.:.||
 Frog   247 QLYSQTSVWLMKTDFVFDYPRPLMPNMVFVGGINCVGEQHLNQEF--EKLVN--SSGEHGFVVFS 307

  Fly   303 LGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFT--AEQVLPENVMIADWWPQQAILHH 365
            ||:.|  :::|..|   .:|:...||.....:.|   .:|  |...|.||..:..|.||..:|.|
 Frog   308 LGSMV--SEIPMNK---AMDIAEALKSIPQKVFW---RYTGKAPPNLGENTHLVKWLPQNDLLAH 364

  Fly   366 PQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIR 430
            |:.:.||:..|...::|.|....|::.:|:..:|...|||::..|..:|:....:..:.|.:.:|
 Frog   365 PKARAFITHAGSHGIYEGICNAVPMVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPEDLSNAVR 429

  Fly   431 QLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVL- 494
            .:..|..|.|.:.::....:.|...|:..||..::.::...||..|:..|:.||:::...:||:
 Frog   430 AVINNPVYKENIQRMSSLHLDRPIHPLDLAVHWVEFVMRHKGAPHLRPAAHDLNWFQYYSLDVIG 494

  Fly   495 LIIAVGFFGILTIPFLAI--C-FILRKSY 520
            .::||    :||..|:::  | |:.|:.:
 Frog   495 FLLAV----LLTALFISLKCCTFVFRRCF 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	120/471 (25%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	137/534 (26%)