Protein Alignment Ugt316A1 and ugt1b3

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001170817.1
• Gene: ugt1b3 / 100384903
• ZFINID: ZDB-GENE-080227-12
• Length: 535
• Species: Danio rerio
• Alignment Length: 565
• Identity: 134/565 - (23%)
• Similarity: 237/565 - (41%)
• Gaps: 104/565 - (18%)

  Fly     4 LQVFLGTLLC---GIVLGANV-------------LTVFPSVWKSHYLFGRRLLQELVESSGNHSV 52
            :.:.||.:.|   |:|..|.|             |.|.| :..||:...:.:.:|:  ....|:|
Zfish     3 INMHLGVIFCLVVGVVCSAAVDQKLSRKSSWTGKLLVVP-MDGSHWTGVKAVAEEM--GRRGHTV 64

  Fly    53 TLISPHAA------QEGVDAEIPKIRELRI--EGLRENWLDMGMSFEAEEMRAQSVMERFTRLIY 109
            .::.|..:      :..:..:.|...:.::  |.|.|:..::.....:......|.|....::..
Zfish    65 IVVIPEISMRLGPGKHYITKKFPVKYDQKLFNEVLTEHVHEVTNPGHSRLKTVTSTMANLLKMFN 129

  Fly   110 AGTTNVDILLSDPQVRKLLTSGEKFDLLIVDLFLSDALLGLAFYYGIPTV--------AVSPTGA 166
            ...:..:.|..|.::.|.|.. |.||.::.|..|....: ||:.:.:|.|        |:..|..
Zfish   130 MMASTSESLFQDKELIKFLRD-ENFDAILTDPALPMGAV-LAYNFSVPAVYMLRGMPCALDATAT 192

  Fly   167 NSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLMS------------TFERLTYNFFHLI 219
                    ..|.:.|..|......|:||:..:|::|.|||            :||.:|.||
Zfish   193 --------ACPNTPSYIPRFHTGNTDRMSFGERVMNVLMSILEQVACKVMYWSFEEVTPNF---- 245

  Fly   220 SQQSVYTNHFELLVKELPLYRD--LTKNLSLA---LINSHPGLHYPRAYLPNMVEVGGLHLSHLN 279
                              |.||  ||:.||..   |:.....|.:|:..:|||..:||::....|
Zfish   246 ------------------LQRDVSLTEILSTGAVWLMRYDFTLEFPKPLMPNMQFIGGINCGVKN 292

  Fly   280 DDNLPKHLLSFME-SAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTA 343
            .  |.|.:..|:. |...|::.||||:.|  :.:|:||..|....|..:.:   .:.|   .:|.
Zfish   293 P--LMKEVEEFVNGSGEHGIVVFSLGSLV--SSMPKEKADIFFKAFSMIPQ---RVLW---RYTG 347

  Fly   344 E--QVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRL 406
            |  ..:||||.:..|.||..:|..|:.:.||:..|...::|.|....|::.:|:..:|.....|:
Zfish   348 EIPNNVPENVKLMKWLPQNDLLGPPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRV 412

  Fly   407 QRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESG 471
            ...||.|.:....:..::||..:..:..|:||.:|:.:|......|...|:..||...:.::...
Zfish   413 ATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHK 477

  Fly   472 GADFLKSHANTLNFWRAEGVDV---LLIIAVGFFGILTIPFLAIC 513
            |||.|:..|:.||:.:...:||   :|:|.:    |:|:..|..|
Zfish   478 GADHLRPAAHELNWLQYHSLDVIGFMLLIVL----IVTLAMLKCC 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	112/490 (23%)
ugt1b3	NP_001170817.1	UDPGT	35..516	CDD:278624	125/529 (24%)