Protein Alignment Ugt316A1 and ugt1b5

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001170813.1
• Gene: ugt1b5 / 100384899
• ZFINID: ZDB-GENE-080227-14
• Length: 528
• Species: Danio rerio
• Alignment Length: 553
• Identity: 136/553 - (24%)
• Similarity: 244/553 - (44%)
• Gaps: 99/553 - (17%)

  Fly    11 LLCGIVLGA--NVLTVFPSVWKSHYLFGRRLLQELVESSGNH--SVTLISPHAAQEG--VDAEIP 69
            |:.|:|..|  |......|.|....|        :|...|:|  .|..::....:.|  |...||
Zfish     8 LVVGVVCSAAMNQKPSRNSSWTGKLL--------VVPMDGSHWTGVKAVAEEMGRRGHTVIVVIP 64

  Fly    70 KIRELRI-----------------EGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDI 117
            :| .:|:                 :.|.:....:..:..|.|   ||:::|.|..||.....||.
Zfish    65 EI-SMRLGPGKHYITKKFPVKYKPDVLNQMIAKLVNTLSAPE---QSLLKRVTSNIYNFGKVVDY 125

  Fly   118 LLSDP----QVRKLL--TSGEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGN 176
            .:|..    |.::|:  ...:.||.::.|..:....: ||:...:|.|.:        |..:...
Zfish   126 FISTTESLFQEQELIEFLRDQNFDAVLTDPAMPTGAI-LAYNLSVPAVYM--------LRGLMCE 181

  Fly   177 PQSSSL-DPSNFLP--FT---ERMNTRQRILNSLMSTFE----RLTYNFFHLISQQSVYTNHFEL 231
            .::::. ||.:::|  ||   :.||..:|::|:|.|..|    :|.::.|..:      |:.|
Zfish   182 SKATACPDPPSYIPRLFTQNSDHMNFGERLMNTLASLMEPLMCKLKFSAFEEV------TSKF-- 238

  Fly   232 LVKELPLYRD--LTKNLSLA---LINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFM 291
                  |:||  :|:.||..   |:.....|.:|:..:||:..:||::....|.  |.|.:..|:
Zfish   239 ------LHRDVSMTEILSTGAVWLMRYDFTLEFPKPLMPNITNIGGINCEVNNP--LTKEVEEFV 295

  Fly   292 E-SAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAE--QVLPENVMI 353
            . |...|::.||||:.|  :.:|:||..|....|..:.:   .:.|   .:|.|  ..:||||.:
Zfish   296 NGSGEHGIVVFSLGSLV--SSMPKEKADIFFKAFSMIPQ---RVLW---RYTGEIPNNVPENVKL 352

  Fly   354 ADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYD 418
            ..|.||..:|.||:.:.||:..|...::|.|....|::.:|:..:|.....|:...||.|.:...
Zfish   353 MKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVGVILSIH 417

  Fly   419 SLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTL 483
            .:..::||..:..:..|:||.:|:.:|......|...|:..||...:.::...|||.|:..|:.|
Zfish   418 DITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAAHEL 482

  Fly   484 NFWRAEGVDV---LLIIAVGFFGILTIPFLAIC 513
            |:.:...:||   :|:|.:    |:|:..|..|
Zfish   483 NWLQYHSLDVIGFMLLIVL----IVTLAMLKCC 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	116/488 (24%)
ugt1b5	NP_001170813.1	UDPGT	30..524	CDD:278624	129/531 (24%)