Protein Alignment Ugt316A1 and ugt2b3

DIOPT Version :10

• Sequence 1: NP_649085.1
• Gene: Ugt316A1 / 40079
• FlyBaseID: FBgn0036842
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001170812.2
• Gene: ugt2b3 / 100384898
• ZFINID: ZDB-GENE-100402-2
• Length: 527
• Species: Danio rerio
• Alignment Length: 567
• Identity: 130/567 - (22%)
• Similarity: 240/567 - (42%)
• Gaps: 102/567 - (17%)

  Fly     1 MQILQVFLGTLL------CGIVLGANVLTVFPSVWK---SHYLFGRRLLQELVESSGNHSVTLIS 56
            |:::..||..|.      ||.:|          ||.   ||::..:.:|..|::.  .|:||::.
Zfish     1 MRLVVCFLSLLTVFSAGQCGNIL----------VWHTEGSHWINLKIVLDTLLDR--GHNVTVLM 53

  Fly    57 PHAA--QEGVDAEIPKIRELRIEGL---RENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVD 116
            |..|  .:..:::....:...:...   .:::||..:.|...||...::::...:....|:.:.|
Zfish    54 PDGALFMKAKESDRFSYQNFSVSTSAQDMQDFLDELLHFSVFEMEQLNLLQIQMKFFDLGSRHQD 118

  Fly   117 I-------LLSDPQVRKLLTSGEKFDLLIVDLF--LSDALLGLAFYYGIPTVAVSPTGANSWLNN 172
            :       :|..|::...|.:| |||:|:.|..  .||.   :|....:|.|..........:..
Zfish   119 MGLSYCDGILKSPELMDKLKTG-KFDVLLSDPMYPCSDI---VAEVLNVPLVFTLRFSIAHTMER 179

  Fly   173 MFGN-PQSSSLDPSNFLPFTERMNTRQRILNSL----MSTFERLTYNFFHLISQQSVYTNHFELL 232
            :.|. |...|..|......|::|:..:||.|:|    |.||..:.:..|     .:.||.:|...
Zfish   180 ICGQIPAPPSYVPGAMSKLTDKMSFTERIFNTLFYLSMDTFSIIAWKKF-----DNYYTEYFGRP 239

  Fly   233 VKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESA-PS 296
            ..    |.::.....:.||.::....:||.::||...:||||.:....  |||.:..|::|: ..
Zfish   240 TS----YCEMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHCTPAKP--LPKDMEEFVQSSGDD 298

  Fly   297 GVIYFSLGADVE-------------TAQLPQEKLAIILDVFGHLKEFHFLLKW----EKEEFTAE 344
            |::.|:||:.::             .||:||:.|                  |    ||.:
Zfish   299 GIVVFTLGSMIDKVPKEMSNRIASALAQIPQKVL------------------WRYGGEKPD---- 341

  Fly   345 QVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRH 409
             .|.||..|..|.||..:|.||:.:.||:..|...::|:|....|::.||:..:|......:...
Zfish   342 -TLGENTRIYKWMPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPLFGDQPDNMVHMTTR 405

  Fly   410 GVSVTV-GYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGA 473
            |.:|.| ...|:....|:..:..:..:.||.|...:|......|...|:.::|..|:.::.:.||
Zfish   406 GAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGA 470

  Fly   474 DFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRKSY 520
            ..|:..|:.|.:::...:||...:..    :||: .|.|||.:.|.:
Zfish   471 KHLRVEAHNLTWYQYHCLDVFAFLTT----VLTL-VLYICFKMAKFF 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt316A1	NP_649085.1	GT1_Gtf-like	19..461	CDD:340817	107/482 (22%)
ugt2b3	NP_001170812.2	UDPGT	20..523	CDD:278624	125/548 (23%)