DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acp76A and Serpinb6e

DIOPT Version :9

Sequence 1:	NP_524153.1	Gene:	Acp76A / 40078	FlyBaseID:	FBgn0015586	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001039000.2	Gene:	Serpinb6e / 435350	MGIID:	2667778	Length:	429	Species:	Mus musculus

Alignment Length:	438	Identity:	83/438 - (18%)
Similarity:	166/438 - (37%)	Gaps:	92/438 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IFLVLCTSLLFQNTIQQNVS------------FQLIREI--DRYTPENFVLS-----VLNIEMIL 52
            ::...|..|||..: :.||.            |.::..|  .|||..:.:|.     .|.:..:|
Mouse     8 LYFPCCICLLFTKS-EHNVGESENSGYILDCVFIMLIVILHSRYTIMDSLLEANATFTLKLFRVL 71

  Fly    53 FEIHAAKAVESNNDLERSL-IINFGYSEARQEVLDWGLRYKKASS--AKFQMANKVAVSQ--KLP 112
            .|..:.....|::.:..|| :|..|.:......:...|...|.|:  |..|...:..:::  |..
Mouse    72 GEDSSKNVFFSSSSMFSSLALILMGANGTTASQISQVLSLDKCSNGGADVQQGFQSLLTEVNKTD 136

  Fly   113 LSQKLRLVNEVLMTSAKKYDVTKDVRPS----------KL------------MDEWLSSHLDGVL 155
            ....||..|::.  |...:|:.:..:.|          ||            ::.|::.....|:
Mouse   137 TGHMLRRANKIF--SDNNFDIMESFKESCYKLYRVEIEKLDFKGTPEQCRQHINAWVAKKTKDVI 199

  Fly   156 ANFVQEKKLNAGENIVAISGMTVTPLWASHFQSEINRYFVNNPGTGYASKDPTCVPMMHSLSSFE 220
            ...:....:|:...::.::.......|...|..|..|.....    .:..:...|.||...|:|:
Mouse   200 RELLSLYTVNSNTRLILVNATYFKGKWEKQFNKEDTREMPFK----VSKNEKKTVQMMSKKSTFK 260

  Fly   221 TMSTDEAKG--IYIPFSSANLGMLILLPRKGVTCKDILDNLNNQIN----VEYN-----DHKDVH 274
            |...:|...  :::|::...|.|:|:||.:.|.    |..:.|||:    :::.     :.::|.
Mouse   261 TYYAEEISTTIVFLPYTDKELSMIIMLPDEQVE----LSMVENQISYKKLIQWTRLVKMEEEEVQ 321

  Fly   275 LLLPIFKEKFDYNIAKFFNGINIEDTFKDSAFKSKAKIKINNFRVNHGIRFQPILRLEVVDDIDT 339
            :.||.||.:..|::......:.:.|.|::|      :...:......|:....::....|:..:.
Mouse   322 VFLPRFKLEATYDMKDVLCKLGMTDAFEES------RADFSGISSKKGLFLSNVVHKSFVEVNEE 380

  Fly   340 G-----KTETFEV-----------NRPFVFVIK-DKI-NVYAVGRIEN 369
            |     .||...|           :|||:|:|: ||. .:..:||..:
Mouse   381 GTEAAVATEIVTVGSPLTQRCLIADRPFLFLIQGDKSKEILFLGRFSS 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acp76A	NP_524153.1	SERPIN	22..367	CDD:294093	78/419 (19%)
Serpinb6e	NP_001039000.2	serpin	53..429	CDD:393296	72/392 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910