Protein Alignment Acp76A and SERPINB1

DIOPT Version :9

• Sequence 1: NP_524153.1
• Gene: Acp76A / 40078
• FlyBaseID: FBgn0015586
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_109591.1
• Gene: SERPINB1 / 1992
• HGNCID: 3311
• Length: 379
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 77/383 - (20%)
• Similarity: 134/383 - (34%)
• Gaps: 81/383 - (21%)

  Fly    53 FEIHAAKAVESNNDLERSLIINFGYSEARQEVLDWGLRYKKASS--------------AKFQM-- 101
            |.:....|:..||......|..|..|.|...|. .|.|...|:.              ::||.
Human    11 FALDLFLALSENNPAGNIFISPFSISSAMAMVF-LGTRGNTAAQLSKTFHFNTVEEVHSRFQSLN 74

  Fly   102 --ANKVAVSQKLPLSQKL------RLVNEVLMTSAKKY----------DVTKDVRPSKLMDEWLS 148
              .||...|..|.|:.:|      ..:.|.|:::.|.|          ..::|.|  |.:::|:.
Human    75 ADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDAR--KTINQWVK 137

  Fly   149 SHLDGVLANFVQEKKLNAGENIVAISGMTVTPLWASHFQSE--INRYFVNNPGTGYASKDPTCVP 211
            ...:|.:...:....::....:|.::.:.....|...|..|  .|..|..|      .||...|.
Human   138 GQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLN------KKDRKTVK 196

  Fly   212 MMHSLSSFETMSTDEAK--GIYIPFSSANLGMLILLP---------RKGVTCKDILDNLNNQINV 265
            ||:....|.....::.|  .:.:|:....|.|:||||         .|.:..:..|:.|:.....
Human   197 MMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKP 261

  Fly   266 EYNDHKDVHLLLPIFKEKFDYNIAKFFNGINIEDTFKDSAFKSKAKIKINNFRVNHGIRFQPILR 330
            |..|..:|::.||.||.:..|.:......:.::|.|..|      |..::.......|....|:.
Human   262 ENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS------KADLSGMSGARDIFISKIVH 320

  Fly   331 LEVVDDIDTG-----------------KTETFEVNRPFVFVIKDKI--NVYAVGRIEN 369
            ...|:..:.|                 ..|.|..:.||:|.|:...  ::..:||..:
Human   321 KSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSS 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acp76A	NP_524153.1	SERPIN	22..367	CDD:294093	76/379 (20%)
SERPINB1	NP_109591.1	SERPIN	4..379	CDD:294093	77/383 (20%)
		CARD-binding motif (CBM). /evidence=ECO:0000269|PubMed:30692621	351..379		7/28 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910