Protein Alignment SmydA-2 and SET5

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_012077.1
• Gene: SET5 / 856614
• SGDID: S000001250
• Length: 526
• Species: Saccharomyces cerevisiae
• Alignment Length: 436
• Identity: 97/436 - (22%)
• Similarity: 164/436 - (37%)
• Gaps: 102/436 - (23%)

  Fly    35 KEHWKKGHRSECQCFEIATNEVLGRHLRATRDIKIGEQILKE-APLVLGPK------VASAPLCL 92
            |.|:.|...|:.:......::..||.|.|.||...|:.|||| .|:|..|.      :::...|.
Yeast   101 KIHFPKALDSDAKVEVKFIDDEHGRGLFAKRDFSKGQIILKENKPIVYIPPLDKLFLISNGKACA 165

  Fly    93 GCHRNL--LAPGKPRGNYHKCSSCSWPLCGKECED---SVH-------HKAECQLMSGSNFQSKI 145
            .|.:.|  |...|...:|..|..|....|.::|:.   |:|       ......::...|::..:
Yeast   166 RCGKALYDLTQHKIMVHYLDCEVCKAIWCSEKCKKAHASLHELLYHSWRSNRIDILHAGNWKRFV 230

  Fly   146 NYVPGEEERKESAYCVIMLLRCM----------------------HLKDKDPDAFLKLYNLED-- 186
            ||.  |:....:|:.|.::...|                      .:|.:|.......::|.:
Yeast   231 NYC--EKYCFTAAFSVGLIYGSMLLDTTGEVKEQWQKLASISQRERIKLRDASGIGSTFSLLNGT 293

  Fly   187 --HLKERLETPLYQVLRANLITFIKTVLGMKDW---------------PEMDILRIAAILDTNTF 234
              |.:|..:....:.:..|:..  :||     |               .|:|..:...::  .||
Yeast   294 TVHTEEESDNGTKKGVEKNIDD--ETV-----WEKCYELFCGAFPKASEEIDFEKFLTMI--GTF 349

  Fly   235 EVRQPRERRKIRALYPGAAMISHDCVPNMR-HRFDDDMNIVFLAKRKIAKGEILSISYTQPLRST 298
            .:.|...:     :|...:.|:|||.||.. .:.::...:...|::.|.|||.:.|:|..||...
Yeast   350 NINQYNGQ-----VYHWISFINHDCEPNAYIEQVEEHEELRLHARKPIKKGEQIRITYVNPLHGV 409

  Fly   299 IQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLKCKAG------KIISLNPLLNSAPWKCQL 357
            ..||..||....|.|.|.|||:  ||.:|.......|..|.      ||.|.:...:.:
Yeast   410 RLRRRELRVNWGFLCQCDRCQN--ELSTFERVPNLEKKNADANLGVEKIDSNDSSEDGS------ 466

  Fly   358 CNFKRSAKDVVTSDAELQQELESLDKTTPVALEEFIYRHRADLHET 403
               |:|..:..:|..|.|.:|:.:.|..    :||    ..|:.||
Yeast   467 ---KKSTGNRKSSMREAQPDLKEILKNG----KEF----ELDIPET 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312	4/10 (40%)
		SET_SMYD	<227..318	CDD:380997	26/91 (29%)
SET5	NP_012077.1	SET	114..>147	CDD:394802	12/32 (38%)
		SET_SMYD	<352..429	CDD:380997	24/81 (30%)