Protein Alignment SmydA-2 and smyd4

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001070062.1
• Gene: smyd4 / 767654
• ZFINID: ZDB-GENE-060929-248
• Length: 753
• Species: Danio rerio
• Alignment Length: 595
• Identity: 116/595 - (19%)
• Similarity: 191/595 - (32%)
• Gaps: 205/595 - (34%)

  Fly     9 CALCQAKASQL--CAACRNVVYCSREHQKEHWKKGHRSECQC-FEIATNEVLGRHLRATRDIKIG 70
            |..|.:::...  |..|....||....||:.|.:.|:.||.. .::....||| ||.....:|.|
Zfish   246 CHHCLSQSLSFVPCPKCSYARYCGESCQKDAWDQWHQWECPVGADLLAIGVLG-HLALRVVLKAG 309

  Fly    71 EQILKEAPLVLGPKVASAPLCLGCHRNLLAPGKPRGNYHKCSSCSWPLCGKECEDSVHHKAECQL 135
                 :..:.:|.|..                |.....:|..|......|.:|..|:.|
Zfish   310 -----QTEVQMGIKNT----------------KDHVTTYKNDSPVQLSLGGDCGKSLDH------ 347

  Fly   136 MSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDPDAFLKLYNLEDHLKERLETPLYQVL 200
                                         ..|.|     ..:::.:|:|..|:.:  .:|..:.|
Zfish   348 -----------------------------TDCFH-----GSSYMGIYSLLPHVAQ--HSPASRFL 376

  Fly   201 RANLITFIKTVL---------------GMK-DW-PEMDILRIAA------------------ILD 230
            .|..:..|...|               |:| .| |||.:|...|                  :.:
Zfish   377 MAITMAVIYGKLQGGPPPNKWMSFKDEGVKASWQPEMSMLGATALRHMMQLRCNAQAITAVRVKE 441

  Fly   231 TNTFEVRQPRERRKIRALYPGAAMISHDCVPN-------------------MRHRFD------DD 270
            .:...|:...|.|...|::|..::::|.|.||                   ....||      ..
Zfish   442 ESGMAVQSSSEIRIATAIFPVLSLLNHSCSPNTSISFTTGFQPDPHNQLGCSEGHFDHPKGSRSG 506

  Fly   271 MNIVFLAKRKIAKGEILSISYTQPLRSTI---QRRVHLRQAKCFDCSCARCQ------DPEELGS 326
            :.:...|.:.:..|:.:...| .|.||.:   :|:..|.:...|.|.|..||      .|.....
Zfish   507 VTVTVRASKDLTAGQEILHCY-GPHRSRMEVKERQRLLLEQYFFQCVCQACQRDLSEGSPNAKEH 570

  Fly   327 FAGAQTCLKCKAGKIISLNPLLNSAPWKCQLCNFKRSAKDVVTSDAELQQELESLDKTTPVALEE 391
            .|....|:||  ||.:..:....:..|..  |..:.|:.||       |..|:...    :.|:|
Zfish   571 TAPGMKCVKC--GKPLQSHTDGYTCSWSS--CGHQISSADV-------QNRLQGFQ----LLLDE 620

  Fly   392 FIYRHRADLHETNTHILQAKY-------------------ALTQLYGSAPGFAMEELSGESLNRK 437
            .::....|......||||:.:                   ||.:||.|...::   |:...|.|.
Zfish   621 AVHLMEQDRLNEALHILQSAFSQANSILTETHPFQGELADALARLYASTGEWS---LAASHLKRS 682

  Fly   438 L------------QLCEELLKLADIF----DGGWSIFRGNLLIDMEEALVTQALRSKDPLDCE-- 484
            |            :|..:|.|||.:.    ||..|:           :::.:|.|... |.|.
Zfish   683 LVAIQAQFGEDSIELGRQLFKLAQLHFNGRDGVASL-----------SVIPRARRLLS-LHCSPR 735

  Fly   485 -EKLRNAAEM 493
             |:|:..:||
Zfish   736 CEELQELSEM 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312	10/38 (26%)
		SET_SMYD	<227..318	CDD:380997	23/136 (17%)
smyd4	NP_001070062.1	NlpI	<65..>134	CDD:443815
		TPR repeat	68..96	CDD:276809
		TPR repeat	101..134	CDD:276809
		zf-MYND	246..285	CDD:460312	10/38 (26%)
		SET_SMYD4	<352..556	CDD:380934	39/211 (18%)
		TPR_12	621..683	CDD:315987	13/64 (20%)